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Clinical Chemistry and Laboratory Medicine (CCLM)

Published in Association with the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM)

Editor-in-Chief: Plebani, Mario

Ed. by Gillery, Philippe / Lackner, Karl J. / Lippi, Giuseppe / Melichar, Bohuslav / Payne, Deborah A. / Schlattmann, Peter / Tate, Jillian R.

12 Issues per year

IMPACT FACTOR 2016: 3.432

CiteScore 2016: 2.21

SCImago Journal Rank (SJR) 2016: 1.000
Source Normalized Impact per Paper (SNIP) 2016: 1.112

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Volume 38, Issue 11 (Nov 2000)


Evaluation of a Fully Automated Assay to Measure C-Telopeptide of Type I Collagen in Serum

Franca Pagani / Graziella Bonetti / Francesca Stefini / Mauro Panteghini
Published Online: 2005-06-01 | DOI: https://doi.org/10.1515/CCLM.2000.166


The measurement of the degradation product of the C-telopeptide of type I collagen in serum (s-βCTX) has been evaluated in the form of an automated chemiluminometric assay. The between-day coefficients of variation ranged between 2.6 and 6.0% over the concentration range 0.12 to 3.25 μg/l. The s-βCTX value correlated well with alternative serum C-telopeptide (r = 0.983) and urine deoxypyridinoline (r = 0.729) measurements. A significant inverse correlation was found between the s-βCTX measurement and creatinine clearance in patients with renal disease.

About the article

Published Online: 2005-06-01

Published in Print: 2000-11-12

Citation Information: Clinical Chemistry and Laboratory Medicine, ISSN (Print) 1434-6621, DOI: https://doi.org/10.1515/CCLM.2000.166.

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