Jump to ContentJump to Main Navigation
Show Summary Details
More options …

Clinical Chemistry and Laboratory Medicine (CCLM)

Published in Association with the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM)

Editor-in-Chief: Plebani, Mario

Ed. by Gillery, Philippe / Greaves, Ronda / Lackner, Karl J. / Lippi, Giuseppe / Melichar, Bohuslav / Payne, Deborah A. / Schlattmann, Peter


IMPACT FACTOR 2018: 3.638

CiteScore 2018: 2.44

SCImago Journal Rank (SJR) 2018: 1.191
Source Normalized Impact per Paper (SNIP) 2018: 1.205

Online
ISSN
1437-4331
See all formats and pricing
More options …
Volume 38, Issue 3

Issues

A New Modular Chemiluminescence Immunoassay Analyser Evaluated

Agostino Ognibene / Christopher J. Drake / Kwan-Yee S. Jeng / Terri E. Pascucci / Stephen Hsu / Francesca Luceri / Gianni Messeri
Published Online: 2005-06-01 | DOI: https://doi.org/10.1515/CCLM.2000.037

Abstract

Thyrotropin (TSH), free thyroxine (fT4) and testosterone assays have been used as a probe to evaluate the performances of a new modular chemiluminescence (CL) immunoassay analyser, the Abbott Architect™ i2000. The evaluation was run in parallel on other systems that use CL as the detection reaction: DPC Immulite®, Chiron Diagnostics ACS-180 and ACS Centaur (TSH functional sensitivity only). TSH functional sensitivity was 0.0012, 0.009, 0.033 and 0.039 mU/l for the Architect, Immulite, ACS Centaur and ACS-180, respectively. Testosterone functional sensitivity was 0.38, 3.7 and 2.0 nmol/l for Architect, Immulite and ACS-180, respectively. Good correlation was obtained between the ACS-180 and Architect for all assays. The Immulite correlation did not agree well with the Architect or ACS-180 for fT4 and testosterone but was in good agreement for TSH. Regarding fT4 and testosterone, equilibrium dialysis and isotopic dilution gas-chromatography mass-spectrometry (GC-MS) respectively were used as reference methods. For both within- and between-run precision, the Architect showed the best reproducibility for all three analytes (CV < 6%).

About the article

Published Online: 2005-06-01

Published in Print: 2000-03-25


Citation Information: Clinical Chemistry and Laboratory Medicine, Volume 38, Issue 3, Pages 251–260, ISSN (Print) 1434-6621, DOI: https://doi.org/10.1515/CCLM.2000.037.

Export Citation

Citing Articles

Here you can find all Crossref-listed publications in which this article is cited. If you would like to receive automatic email messages as soon as this article is cited in other publications, simply activate the “Citation Alert” on the top of this page.

[1]
Elaine Murphy, Claus C. Glüer, David M. Reid, Dieter Felsenberg, Christian Roux, Richard Eastell, and Graham R. Williams
The Journal of Clinical Endocrinology & Metabolism, 2010, Volume 95, Number 7, Page 3173
[2]
Belma Gjergjizi, Ferah Çoğun, Ender Yıldırım, Merve Eryılmaz, Yeşim Selbes, Necdet Sağlam, and Uğur Tamer
Sensors and Actuators B: Chemical, 2018
[3]
Osvaldo P Almeida, Anna Waterreus, Nigel Spry, Leon Flicker, and Ralph N Martins
Psychoneuroendocrinology, 2004, Volume 29, Number 8, Page 1071
[4]
Younhee Park, Yongjung Park, Jungyong Park, and Hyon-Suk Kim
Yonsei Medical Journal, 2012, Volume 53, Number 3, Page 557
[6]
H. F. Escobar-Morreale, E. Carmina, D. Dewailly, A. Gambineri, F. Kelestimur, P. Moghetti, M. Pugeat, J. Qiao, C. N. Wijeyaratne, S. F. Witchel, and R. J. Norman
Human Reproduction Update, 2012, Volume 18, Number 2, Page 146
[7]
Walter Hubl, Martina Zogbaum, James C. Boyd, John Savory, Mary Schubert, Dirk Meyer, and Thomas Demant
Clinica Chimica Acta, 2005, Volume 357, Number 1, Page 43
[8]
Gurdeep Singh Dhatt, Ravichandra Jayasundaram, Laila Abdul Wareth, Nico Nagelkerke, Krishnasamy Jayasundaram, Etidal Ali Darwish, and Anselma Lewis
Clinica Chimica Acta, 2006, Volume 370, Number 1-2, Page 147
[9]
Pei-Shan Tsai, Chang-Jung Chang, Kow-Tong Chen, Kuo-Chin Chang, Shu-Fen Hung, Jing-Houng Wang, Chao-Hung Hung, Chien-Hung Chen, Po-Lin Tseng, Kwong-Ming Kee, Yi-Hao Yen, Chin-Chen Tsai, and Sheng-Nan Lu
Liver International, 2011, Volume 31, Number 7, Page 971
[10]
Chien-Hung Chen, Chuan-Mo Lee, Jing-Houng Wang, Hung-Da Tung, Chao-Hung Hung, and Sheng-Nan Lu
European Journal of Gastroenterology & Hepatology, 2004, Volume 16, Number 11, Page 1213
[12]
Hyun Ju Sung, Jeong-Ho Kim, Rojin Park, Kyung Ryul Lee, and Oh Hun Kwon
Clinical Chemistry and Laboratory Medicine, 2002, Volume 40, Number 8

Comments (0)

Please log in or register to comment.
Log in