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Clinical Chemistry and Laboratory Medicine (CCLM)

Published in Association with the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM)

Editor-in-Chief: Plebani, Mario

Ed. by Gillery, Philippe / Greaves, Ronda / Lackner, Karl J. / Lippi, Giuseppe / Melichar, Bohuslav / Payne, Deborah A. / Schlattmann, Peter

IMPACT FACTOR 2018: 3.638

CiteScore 2018: 2.44

SCImago Journal Rank (SJR) 2018: 1.191
Source Normalized Impact per Paper (SNIP) 2018: 1.205

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Volume 38, Issue 4


Use of Ion-Selective Electrodes for Blood-Electrolyte Analysis. Recommendations for Nomenclature, Definitions and Conventions

Robert W. Burnett / Arthur K. Covington / Nils Fogh-Andersen / Wolf R. Külpmann / Andrzej Lewenstam / Anton H.J. Maas / Oswald Müller-Plathe / Antonius L. VanKessel / Willem G. Zijlstra
Published Online: 2005-06-01 | DOI: https://doi.org/10.1515/CCLM.2000.052


This paper will familiarize the reader with the terms used to describe the behavior of ion-selective electrodes, particularly in relation to their use in clinical chemistry for determination of blood electrolyte cations. It serves as an introduction to a series of papers dealing with important cations in blood, namely calcium, sodium, and potassium. The detailed relationships between the ion activity determined by means of ion-selective electrode potentiometry in undiluted specimens, and the total substance concentration measured by flame atomic-emission spectrometry are described by flow chart and equations. Adoption of a convention for reporting results is recommended.

The Working Group on Selective Electrodes has taken into account recent revisions of IUPAC recommendations on nomenclature and selectivity coefficient determinations for ion-selective electrodes, and benefited from the experience of a member of the WG, who was also involved in the IUPAC discussions. Nomenclature for determined quantities follows previous IUPAC/IFCC joint recommendations.

About the article

Published Online: 2005-06-01

Published in Print: 2000-04-30

Citation Information: Clinical Chemistry and Laboratory Medicine, Volume 38, Issue 4, Pages 363–370, ISSN (Print) 1434-6621, DOI: https://doi.org/10.1515/CCLM.2000.052.

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