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Clinical Chemistry and Laboratory Medicine (CCLM)

Published in Association with the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM)

Editor-in-Chief: Plebani, Mario

Ed. by Gillery, Philippe / Lackner, Karl J. / Lippi, Giuseppe / Melichar, Bohuslav / Payne, Deborah A. / Schlattmann, Peter / Tate, Jillian R.

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Volume 39, Issue 10 (Oct 2001)


Identifying Bacteria in Human Urine: Current Practice and the Potential for Rapid, Near-Patient Diagnosis by Sensing Volatile Organic Compounds

Nicolas Guernion / Norman M. Ratcliffe / Peter T.N. Spencer-Phillips / Robin A. Howe
Published Online: 2005-06-01 | DOI: https://doi.org/10.1515/CCLM.2001.146


Urinary tract infection (UTI) represents a significant burden for the National Health Service. Extensive research has been directed towards rapid detection of UTI in the last thirty years. A wide range of microbiological and chemical techniques are now available to identify and quantify bacteria in urine. However, there is a clear and present need for near, rapid, sensitive, reliable analytical methods, preferably with low-running costs, that could allow early detection of UTI and other diseases in urine. Here we review the “state of the art” of current practice for the detection of bacteria in urine and describe the advantages of the recent “e-nose” technology as a potential tool for rapid, near-patient diagnosis of UTI, by sensing volatile organic compounds (VOCs).

About the article

Published Online: 2005-06-01

Published in Print: 2001-10-23

Citation Information: Clinical Chemistry and Laboratory Medicine, ISSN (Print) 1434-6621, DOI: https://doi.org/10.1515/CCLM.2001.146. Export Citation

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