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Clinical Chemistry and Laboratory Medicine (CCLM)

Published in Association with the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM)

Editor-in-Chief: Plebani, Mario

Ed. by Gillery, Philippe / Lackner, Karl J. / Lippi, Giuseppe / Melichar, Bohuslav / Payne, Deborah A. / Schlattmann, Peter / Tate, Jillian R.

12 Issues per year

IMPACT FACTOR 2016: 3.432

CiteScore 2016: 2.21

SCImago Journal Rank (SJR) 2016: 1.000
Source Normalized Impact per Paper (SNIP) 2016: 1.112

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Volume 39, Issue 3


IFCC Reference Measurement Procedure for Substance Concentration Determination of Total Carbon Dioxide in Blood, Plasma or Serum

Robert W. Burnett / Arthur K. Covington / Niels Fogh-Andersen / Wolf R. Külpmann / Andrzej Lewenstam / Anton H. J. Maas / Antonius L. VanKessel / Willem G. Zijlstra
Published Online: 2005-07-27 | DOI: https://doi.org/10.1515/cclm.2001.39.3.283


A reference measurement procedure for substance concentration determination of total CO2 in blood, plasma (the anticoagulant is usually heparin) or serum is described. The document covers the principle of the method, the materials and equipment needed and essential aspects of the procedure. The substance concentration of total CO2 in blood, plasma or serum is accurately determined and therefore this procedure is recommended for assigning reference values to reference materials and for blood gas quality assurance in laboratories and by manufacturers of blood gas equipment.

About the article

Published Online: 2005-07-27

Published in Print: 2001-04-09

Citation Information: Clinical Chemistry and Laboratory Medicine, Volume 39, Issue 3, Pages 283–289, ISSN (Print) 1434-6621, DOI: https://doi.org/10.1515/cclm.2001.39.3.283.

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