Jump to ContentJump to Main Navigation
Show Summary Details

Clinical Chemistry and Laboratory Medicine (CCLM)

Published in Association with the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM)

Editor-in-Chief: Plebani, Mario

Ed. by Gillery, Philippe / Lackner, Karl J. / Lippi, Giuseppe / Melichar, Bohuslav / Payne, Deborah A. / Schlattmann, Peter / Tate, Jillian R.

IMPACT FACTOR increased in 2015: 3.017
Rank 5 out of 30 in category Medical Laboratory Technology in the 2014 Thomson Reuters Journal Citation Report/Science Edition

SCImago Journal Rank (SJR) 2015: 0.873
Source Normalized Impact per Paper (SNIP) 2015: 0.982
Impact per Publication (IPP) 2015: 2.238

See all formats and pricing


Select Volume and Issue


30,00 € / $42.00 / £23.00

Get Access to Full Text

Performance Evaluation of the Precision™ PCx™ Point-of-Care Blood Glucose Analyzer Using Discriminant Ratio Methodology

Véronique Y. Miendje Deyi / Marianne Philippe / Kathy C. Alexandre / Philippe De Nayer / Michel P. Hermans

Citation Information: Clinical Chemistry and Laboratory Medicine. Volume 40, Issue 10, Pages 1052–1055, ISSN (Print) 1434-6621, DOI: https://doi.org/10.1515/CCLM.2002.184, June 2005

Publication History

Published Online:


Point-of-care glucose testing needs to be integrated into a laboratory information system to provide continuous care. Selecting a particular glucose monitoring system is based on both analytical performance and on user's preference. We evaluated accuracy, performance and regulatory compliance of the Precision™ PCx™ glucose analyzer (Abbott), with automatic download into a central station, for remote quality control (QC) management and automatic upgrading. We used the discriminant ratio (DR) methodology, which determines the DR of a test (e.g. the ratio between the underlying SD and the within-subject SD), and compares it to that of another test allegedly measuring the same parameter. Accuracy was evaluated by Clarke's error grid method. Seven hundred and ninety four blood samples were taken from 22 diabetic patients, combined with two capillary blood samples: one for analysis by reference method and the second for PCx™ analysis. Linear regression analysis revealed, over a 2.1 to 26.9 mmol/l glucose concentration range, a correlation coefficient of 0.963, an intercept of 0.7 mmol/l and a slope of 0.851. Mean difference between meter-generated results and the reference method was −7.1±10.8%. Between-run imprecision for PCx™ using Abbott's controls at low and mid-low concentrations was 5.4 and 3.8%, respectively. Clarke's error grid did not show any clinical impact related to difference between methods. DRs were of similar magnitude using both methods. Nursing staff found PCx™ easy for everyday use. Our data show that PCx™ results agree with those obtained with the reference method, as shown by lack of significant difference in DRs, and by excellent correlation.

Citing Articles

Here you can find all Crossref-listed publications in which this article is cited. If you would like to receive automatic email messages as soon as this article is cited in other publications, simply activate the “Citation Alert” on the top of this page.

Manuel Salvador Rodríguez-Oliva, Catalina Sánchez-Mora, María del Pilar Carrascosa-Salmoral, María Francisca Fernández-Gallardo, Víctor Sánchez-Margalet, and Raimundo Goberna-Ortiz
Revista del Laboratorio Clínico, 2008, Volume 1, Number 2, Page 48
Hubert W. Vesper, Enada Archibold, and Gary L. Myers
Clinica Chimica Acta, 2005, Volume 358, Number 1-2, Page 68
Cheng-Teng Hsu, Hung-Chan Hsiao, Ming-Shih Lee, Shuo-Fen Chang, Tsung-Chien Lee, Yang-Sheng Tsai, and Jyh-Myng Zen
Clinica Chimica Acta, 2009, Volume 402, Number 1-2, Page 119
Brad S. Karon, Laurie Griesmann, Renee Scott, Sandra C. Bryant, Jeffrey A. Dubois, Terry L. Shirey, Steven Presti, and Paula J. Santrach
Diabetes Technology & Therapeutics, 2008, Volume 10, Number 2, Page 111
Víctor Sánchez-Margalet, Manuel Rodriguez-Oliva, Cristina Sánchez-Pozo, María Francisca Fernández-Gallardo, and Raimundo Goberna
Clinical Chemical Laboratory Medicine, 2005, Volume 43, Number 8
George A Jelinek, Tracey J Weiland, Gaye Moore, Grace Tan, Marg Maslin, Kath Bowman, Glenn Ward, and Kerin O'Dea
Emergency Medicine Australasia, 2010, Volume 22, Number 5, Page 427

Comments (0)

Please log in or register to comment.