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Clinical Chemistry and Laboratory Medicine (CCLM)

Published in Association with the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM)

Editor-in-Chief: Plebani, Mario

Ed. by Gillery, Philippe / Lackner, Karl J. / Lippi, Giuseppe / Melichar, Bohuslav / Payne, Deborah A. / Schlattmann, Peter / Tate, Jillian R.


IMPACT FACTOR increased in 2015: 3.017
Rank 5 out of 30 in category Medical Laboratory Technology in the 2014 Thomson Reuters Journal Citation Report/Science Edition

SCImago Journal Rank (SJR) 2015: 0.873
Source Normalized Impact per Paper (SNIP) 2015: 0.982
Impact per Publication (IPP) 2015: 2.238

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1437-4331
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Outcomes of Continuous Process Improvement of a Nutritional Care Program Incorporating TTR Measurement

Elia Mears

Citation Information: Clinical Chemistry and Laboratory Medicine. Volume 40, Issue 12, Pages 1355–1359, ISSN (Print) 1434-6621, DOI: 10.1515/CCLM.2002.234, June 2005

Publication History

Published Online:
2005-06-01

Abstract

Early assessment of protein calorie malnutrition (PCM) can improve the outcome for hospitalized patients by allowing the initiation of nutrition support if required. In addition, monitoring nutritional status during the hospital stay can identify a decline in or improvement of PCM so that alterations to treatment regimens can be made if needed. The visceral protein albumin is the traditional laboratory indicator of PCM. In the past decade another protein has been lauded as a superior marker that can be used in conjunction. We undertook several studies to test the effectiveness of TTR as an aid in nutritional assessment. We found TTR to be a sensitive measure of nutritional status, allowing for earlier assessment and intervention, thus reducing length of stay and other hospital associated costs. Based on these findings, our hospital generated and implemented a multidisciplinary nutrition care program. Transthyretin is an integral portion of this program; levels are determined on admission and repeated twice weekly until discharge.

Citing Articles

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[1]
Fabrizio Gallo, Enrico Haupt, Gian Luigi Devoto, Concetta Marchello, Roberta Garbarini, Maura Ferrari Bravo, Roberta Boicelli, Franca Deiana, and Omar Racchi
Mediterranean Journal of Nutrition and Metabolism, 2011, Volume 4, Number 3, Page 191
[2]
A.M. Moghazy, O.A. Adly, A.H. Abbas, T.A. Moati, O.S. Ali, and B.A. Mohamed
Burns, 2010, Volume 36, Number 4, Page 495

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