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Clinical Chemistry and Laboratory Medicine (CCLM)

Published in Association with the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM)

Editor-in-Chief: Plebani, Mario

Ed. by Gillery, Philippe / Greaves, Ronda / Lackner, Karl J. / Lippi, Giuseppe / Melichar, Bohuslav / Payne, Deborah A. / Schlattmann, Peter

IMPACT FACTOR 2018: 3.638

CiteScore 2018: 2.44

SCImago Journal Rank (SJR) 2018: 1.191
Source Normalized Impact per Paper (SNIP) 2018: 1.205

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Volume 41, Issue 2


Glutathione Peroxidase Activity and Serum Selenium Concentration in Intrinsic Asthmatic Patients

Durdi Qujeq / Behzad Hidari / Khezroolla Bijani / Hosein Shirdel
Published Online: 2005-06-01 | DOI: https://doi.org/10.1515/CCLM.2003.032


Serum glutathione peroxidase (GSH-Px) activity and selenium concentration were compared in intrinsic asthmatic patients and non-asthmatic control subjects. Serum GSH-Px activity and selenium concentration were assessed in 46 asthmatic patients and 75 age- and sex-matched non-asthmatic subjects by spectrophotometric assay. Mean serum GSH-Px activity was lower in intrinsic asthmatic subjects (9.4±2.6 μmol NADPH oxidized/min/g of protein) than in non-asthmatic subjects (16.3±2.9 μmol NADPH oxidized/min/g of protein). Mean serum selenium was lower in intrinsic asthmatic subjects (1.15±0.23 μM) than in non-asthmatic subjects (1.98±0.27 μM). Asthmatic patients have significantly lower concentration of selenium and GSH-Px activity measured in serum.

About the article

Published Online: 2005-06-01

Published in Print: 2003-02-21

Citation Information: Clinical Chemistry and Laboratory Medicine, Volume 41, Issue 2, Pages 200–202, ISSN (Print) 1434-6621, DOI: https://doi.org/10.1515/CCLM.2003.032.

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