Jump to ContentJump to Main Navigation
Show Summary Details
More options …

Clinical Chemistry and Laboratory Medicine (CCLM)

Published in Association with the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM)

Editor-in-Chief: Plebani, Mario

Ed. by Gillery, Philippe / Lackner, Karl J. / Lippi, Giuseppe / Melichar, Bohuslav / Payne, Deborah A. / Schlattmann, Peter / Tate, Jillian R.

12 Issues per year

IMPACT FACTOR 2016: 3.432

CiteScore 2016: 2.21

SCImago Journal Rank (SJR) 2016: 1.000
Source Normalized Impact per Paper (SNIP) 2016: 1.112

See all formats and pricing
More options …
Volume 41, Issue 8 (Aug 2003)


Biofactors in the Mediterranean Diet

Mariette Gerber
Published Online: 2005-06-01 | DOI: https://doi.org/10.1515/CCLM.2003.153


This Review covers the sources and the main effects on human health of well-known micronutrients such as minerals and vitamins and also of microconstituents contained in the Mediterranean diet. Vitamins were first identified because of deficiency diseases still present in certain parts of the world. Hydrosoluble vitamins, among them folic acid and vitamin C, also play a role in chronic degenerative diseases, not only the main cause of mortality in the Western world but also increasingly common in developing countries. Hydrosoluble vitamins are well represented in the Mediterranean diet, more so than vitamin A, a liposoluble vitamin obtained primarily from animal foods. Vitamin E is important for antioxidant and cellular functions. The Mediterranean diet is also rich in provitamins A, such as α-and β-carotene and β-cryptoxanthine. Microconstituents are non-nutritional compounds known to protect plants and more recently suspected to have a protective effect in humans. They play a role in the antioxidant defense of the organism, but their effect on various enzyme activities appears even more promising and is still under investigation. It is nevertheless difficult to isolate the effect of the numerous biofactors present in the Mediterranean diet from the foods themselves, especially because of the possible synergy between the various biofactors.

About the article

Published Online: 2005-06-01

Published in Print: 2003-08-07

Citation Information: Clinical Chemistry and Laboratory Medicine, ISSN (Print) 1434-6621, DOI: https://doi.org/10.1515/CCLM.2003.153.

Export Citation

Citing Articles

Here you can find all Crossref-listed publications in which this article is cited. If you would like to receive automatic email messages as soon as this article is cited in other publications, simply activate the “Citation Alert” on the top of this page.

Maria G. Kakkoura, Kleitos Sokratous, Christiana A. Demetriou, Maria A. Loizidou, Giorgos Loucaides, Eleni Kakouri, Andreas Hadjisavvas, and Kyriacos Kyriacou
Molecular Nutrition & Food Research, 2017, Volume 61, Number 4, Page 1600558
Maria G. Kakkoura, Maria A. Loizidou, Christiana A. Demetriou, Giorgos Loucaides, Maria Daniel, Kyriacos Kyriacou, and Andreas Hadjisavvas
European Journal of Nutrition, 2017, Volume 56, Number 2, Page 545
Hiu Yee Kwan, Xiaojuan Chao, Tao Su, Xiuqiong Fu, Anfernee Kai Wing Tse, Wang Fun Fong, and Zhi-Ling Yu
Critical Reviews in Food Science and Nutrition, 2015, Page 00
Mónica Sousa, Vítor H. Teixeira, and José Soares
International Journal of Food Sciences and Nutrition, 2014, Volume 65, Number 2, Page 151
J. Hernandez-Elizondo, C. Monteagudo, M.A. Murcia, N. Olea, F. Olea-Serrano, and M. Mariscal-Arcas
Food Additives & Contaminants: Part A, 2013, Volume 30, Number 4, Page 627
Yuqing Dong, Sujay Guha, Xiaoping Sun, Min Cao, Xiaoxia Wang, and Sige Zou
Oxidative Medicine and Cellular Longevity, 2012, Volume 2012, Page 1
Ana Cañuelo, Bienvenida Gilbert-López, Pedro Pacheco-Liñán, Esther Martínez-Lara, Eva Siles, and Antonio Miranda-Vizuete
Mechanisms of Ageing and Development, 2012, Volume 133, Number 8, Page 563
Mary Ann Lila and Ilya Raskin
Journal of Food Science, 2005, Volume 70, Number 1, Page R20
Karina de la Torre-Carbot, Jorge L. Chávez-Servín, Olga Jaúregui, Ana I. Castellote, Rosa M. Lamuela-Raventós, Montserrat Fitó, María-Isabel Covas, Daniel Muñoz-Aguayo, and M. Carmen López-Sabater
Analytica Chimica Acta, 2007, Volume 583, Number 2, Page 402
Valeria Pala, Sabina Sieri, Giovanna Masala, Domenico Palli, Salvatore Panico, Paolo Vineis, Carlotta Sacerdote, Amalia Mattiello, Rocco Galasso, Simonetta Salvini, Marco Ceroti, Franco Berrino, Elisabetta Fusconi, Rosario Tumino, Graziella Frasca, Elio Riboli, Antonia Trichopoulou, Nikolaos Baibas, and Vittorio Krogh
Nutrition, Metabolism and Cardiovascular Diseases, 2006, Volume 16, Number 3, Page 186
Damien Bouvier, Vincent Sapin, Michèle Bonnard-Gougeon, and Geoffroy Marceau
Clinical Chemistry and Laboratory Medicine, 2010, Volume 48, Number 5
Mariette Gerber, Anne Thiébaut, Pierre Astorg, Françoise Clavel-Chapelon, and Nicole Combe
European Journal of Lipid Science and Technology, 2005, Volume 107, Number 7-8, Page 540
R. L. Kennedy, K. Chokkalingam, and H. R. Farshchi
Diabetic Medicine, 2005, Volume 22, Number 7, Page 821

Comments (0)

Please log in or register to comment.
Log in