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Clinical Chemistry and Laboratory Medicine (CCLM)

Published in Association with the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM)

Editor-in-Chief: Plebani, Mario

Ed. by Gillery, Philippe / Lackner, Karl J. / Lippi, Giuseppe / Melichar, Bohuslav / Payne, Deborah A. / Schlattmann, Peter / Tate, Jillian R.

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Online
ISSN
1437-4331
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Volume 42, Issue 12 (Dec 2004)

Issues

The relationship between cryoglobulins and HCV-RNA in the serum of patients infected with different HCV genotypes

Toshio Okazaki
  • Department of Forensic Medicine and Science, Kitasato University Graduate School of Medical Sciences, Sagamihara, Japan and Department of Hematological Informatics, Kitasato University School of Allied Health Sciences, Sagamihara, Japan
/ Toshiaki Nagai
  • Department of Legal Medicine, Dokkyo University School of Medicine, Mibu, Japan
/ Tatsuo Nagai
  • Department of Forensic Medicine and Science, Kitasato University Graduate School of Medical Sciences, Sagamihara, Japan and Department of Hematological Informatics, Kitasato University School of Allied Health Sciences, Sagamihara, Japan
Published Online: 2011-09-21 | DOI: https://doi.org/10.1515/CCLM.2004.270

References

  • 1

    McOmish F, Yap PL, Dow BC, Follett EA, Seed C, et al. Geographical distribution of hepatitis C virus genotypes in blood donors: an international collaborative survey. J Clin Microbiol 1994; 32:884–92.

  • 2

    Agha S, Tanaka Y, Saudy N, Kurbanov F, Abo-Zeid M, et al. Reliability of hepatitis C virus core antigen assay for detection of viremia in HCV genotype 1, 2, 3, and 4 infected blood donors: a collaborative study between Japan, Egypt, and Uzbekistan. J Med Virol 2004; 73:216–22. [Crossref]

  • 3

    Enomoto N, Sakuma I, Asahina Y, Kurosaki M, Murakami T, et al. Comparison of full-length sequences of interferon-sensitive and resistant hepatitis C virus 1b. Sensitivity to interferon is conferred by amino acid substitutions in the NS5A region. J Clin Invest 1995; 96:224–30. [Crossref]

  • 4

    Okuse C, Yotsuyanagi H, Okazaki T, Yasuda K, Fujioka T, et al. Detection, using a novel method, of a high prevalence of cryoglobulinemia in persistent hepatitis C virus infection. Hepatol Res 2003; 27:18–22.

  • 5

    Disdier P, Harle J-R, Weiller PJ. Cryoglobulinemia and hepatitis C infection. Lancet 1991; 338:1151–2.

  • 6

    Nagai T, Okazaki T. Analysis of gammaglobulins consisting of hepatitis C-associated cryoglobulins in the blood. Clin Chem Lab Med 2004. In press. [Crossref]

  • 7

    Agnello V, Chung RT, Kaplan LM. A role for hepatitis C virus infection in type II cryoglobulinemia. N Engl J Med 1992; 327:1490–5.

  • 8

    Okazaki T, Nagai T, Nagai T. Relationship between cryoglobulins and hepatitis C virus (HCV) core antigen or antibody titers. Clin Chem Lab Med 2004; 42:105–6.

  • 9

    Nagai T, Fujioka T, Okazaki T. Hepatitis C-associated complement cold activation. Clin Chem Lab Med 2004; 42:1447–1448.

  • 10

    Valcavi P, Medici MC, Casula F, Arcangeletti MC, De Conto F, Pinardi F, et al. Evaluation of a total hepatitis C virus (HCV) core antigen assay for the detection of antigenaemia in anti-HCV positive individuals. J Med Virol 2004; 73:397–403. [Crossref]

  • 11

    Okazaki T, Nagai T, Kanno T. Gel diffusion procedure for the detection of cryoglobulins in serum. Clin Chem 1998; 44:1558–9.

About the article

Corresponding author. Toshio Okazaki, PhD, Department of Forensic Medicine and Science, Kitasato University Graduate School of Medical Sciences, Kitasato 1-15-1, Sagamihara-shi, Kanagawa Prefecture 228-8555, Japan


Published Online: 2011-09-21

Published in Print: 2004-12-01


Citation Information: Clinical Chemistry and Laboratory Medicine (CCLM), ISSN (Online) 1437-4331, ISSN (Print) 1434-6621, DOI: https://doi.org/10.1515/CCLM.2004.270. Export Citation

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[1]
Toshio Okazaki, Toshiaki Nagai, and Tatsuo Nagai
Clinical Chemical Laboratory Medicine, 2004, Volume 42, Number 12

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