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Clinical Chemistry and Laboratory Medicine (CCLM)

Published in Association with the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM)

Editor-in-Chief: Plebani, Mario

Ed. by Gillery, Philippe / Lackner, Karl J. / Lippi, Giuseppe / Melichar, Bohuslav / Payne, Deborah A. / Schlattmann, Peter / Tate, Jillian R.

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Volume 42, Issue 5 (May 2004)


Amphetamines and 3,4-methylendioxymetamphetamine (MDMA): evaluation of KIMS (kinetic interaction of microparticles in solution) assay at two cut-off levels

Lucio Marchioro / Flavia Bassetto / Giuliano Dall'Olio / Luciano Tedeschi / Franca Castagna / Mario Plebani
Published Online: 2005-06-01 | DOI: https://doi.org/10.1515/CCLM.2004.092


Two screening methods for the assay of amphetamines and their derivatives have been applied to the same analytical instrument for their evaluation. In addition to an assay at a cut-off of 1000 μg/l, a new specific reagent was evaluated for an ultra-sensitive assay of amphetamines and 3,4-methylendioxyme-tamphetamine with a cut-off of 300 μg/l. The assay confirmation was performed using high-performance liquid chromatography and gas chromatography/mass spectrometry techniques. The results were positive for both screening methods, confirming the efficacy of two simultaneous methods with different cut-off levels.

About the article

Published Online: 2005-06-01

Published in Print: 2004-05-10

Citation Information: Clinical Chemistry and Laboratory Medicine (CCLM), ISSN (Online) 1437-4331, ISSN (Print) 1434-6621, DOI: https://doi.org/10.1515/CCLM.2004.092. Export Citation

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