Jump to ContentJump to Main Navigation
Show Summary Details

Clinical Chemistry and Laboratory Medicine (CCLM)

Published in Association with the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM)

Editor-in-Chief: Plebani, Mario

Ed. by Gillery, Philippe / Lackner, Karl J. / Lippi, Giuseppe / Melichar, Bohuslav / Payne, Deborah A. / Schlattmann, Peter / Tate, Jillian R.

IMPACT FACTOR increased in 2015: 3.017
Rank 5 out of 30 in category Medical Laboratory Technology in the 2014 Thomson Reuters Journal Citation Report/Science Edition

SCImago Journal Rank (SJR) 2015: 0.873
Source Normalized Impact per Paper (SNIP) 2015: 0.982
Impact per Publication (IPP) 2015: 2.238

See all formats and pricing


Select Volume and Issue


30,00 € / $42.00 / £23.00

Get Access to Full Text

Laboratory network of excellence: enhancing patient safety and service effectiveness

Mario Plebani1 / Ferruccio Ceriotti2 / Gianni Messeri3 / Cosimo Ottomano4 / Nicola Pansini5 / Pierangelo Bonini6







Corresponding author: Prof. Dr. Mario Plebani, Department of Laboratory Medicine, University Hospital of Padova, Via Nicolo Giustiniani 2, 35131 Padova, Italy

Citation Information: Clinical Chemical Laboratory Medicine. Volume 44, Issue 2, Pages 150–160, ISSN (Online) 1437-4331, ISSN (Print) 1434-6621, DOI: https://doi.org/10.1515/CCLM.2006.028, February 2006

Publication History

September 8, 2005
November 16, 2005
Published Online:


Clinical laboratories have undergone major changes due to technological progress and economic pressure. While costs of laboratory testing continue to be the dominant issue within the healthcare service worldwide, quality, effectiveness and impact on outcomes are also emerging as critical value-added features. Five Italian laboratories are therefore promoting a network of excellence by investigating markers of effectiveness of laboratory services and sharing their experience of using them in clinical practice. In the present study we report preliminary data on indicators of quality in all phases of the so-called total testing process, the key to evaluating all phases of the total testing process, including the appropriateness of test requests and data interpretation. Initial findings in evaluating pre-analytical causes of specimen rejection in three different laboratories and the effects of introducing three laboratory clinical guidelines are reported. These data should stimulate debate in the scientific community and encourage more clinical laboratories to use the same indicators to improve clinical effectiveness and clinical outcomes within the healthcare service.

Keywords: clinical outcomes; errors and risk of error; laboratory network; patient safety quality indicators; total testing process

Citing Articles

Here you can find all Crossref-listed publications in which this article is cited. If you would like to receive automatic email messages as soon as this article is cited in other publications, simply activate the “Citation Alert” on the top of this page.

Jose L. Andrade-Pineda, Pedro L. Gonzalez-R, and Jose M. Framinan
Interfaces, 2013, Volume 43, Number 4, Page 360
M. Plebani, L. Sciacovelli, A. Aita, A. Padoan, and M.L. Chiozza
Clinica Chimica Acta, 2014, Volume 432, Page 44
Ángeles Giménez Marín, Pedro Molina Mendoza, José Joaquin Ruiz Arredondo, Federico Acosta González, Marisa López Pérez, Manolo Jiménez Cueva, Teresa Cueto Santamaría, Rosa Olmedo Sánchez, Mercedes López Somosierras, Francisco Rivas Ruiz, and María del Mar Pérez Hidalgo
Revista del Laboratorio Clínico, 2010, Volume 3, Number 4, Page 161
Stephen D. Krau
Critical Care Nursing Clinics of North America, 2010, Volume 22, Number 1, Page 1
Maria Salinas La Casta, Emilio Flores Pardo, and Joaquín Uris Selles
Gaceta Sanitaria, 2009, Volume 23, Number 3, Page 250
Alexandre C. Guimarães, Marilei Wolfart, Maria L.L. Brisolara, and Caroline Dani
Clinical Biochemistry, 2012, Volume 45, Number 1-2, Page 123
Laura Sciacovelli, Oswald Sonntag, Andrea Padoan, Carlo Federico Zambon, Paolo Carraro, and Mario Plebani
Clinical Chemistry and Laboratory Medicine, 2012, Volume 50, Number 3
Giuseppe Lippi, Roberto Fostini, and Gian Cesare Guidi
Clinics in Laboratory Medicine, 2008, Volume 28, Number 2, Page 285
Mario Plebani
Clinica Chimica Acta, 2009, Volume 404, Number 1, Page 59
Giuseppe Lippi and Gian Cesare Guidi
The American Journal of Emergency Medicine, 2008, Volume 26, Number 3, Page 373
Johan Söderberg, Kjell Grankvist, Christine Brulin, and Olof Wallin
Scandinavian Journal of Clinical & Laboratory Investigation, 2009, Volume 69, Number 7, Page 731
Giuseppe Lippi, Norbert Blanckaert, Pierangelo Bonini, Sol Green, Steve Kitchen, Vladimir Palicka, Anne J. Vassault, Camilla Mattiuzzi, and Mario Plebani
Clinical Chemistry and Laboratory Medicine, 2009, Volume 47, Number 2
Mario Plebani and Elisa Piva
Journal of Medical Biochemistry, 2010, Volume 29, Number 4
César Alex de Oliveira Galoro, Maria Elizabete Mendes, and Marcelo Nascimento Burattini
Benchmarking: An International Journal, 2009, Volume 16, Number 6, Page 817
Ingolf Schimke
Analytical and Bioanalytical Chemistry, 2009, Volume 393, Number 5, Page 1499
Gustáv Kováč and Anna Porubenová
Accreditation and Quality Assurance, 2008, Volume 13, Number 3, Page 165
Giuseppe Lippi, Gian Luca Salvagno, Martina Montagnana, Franco Manzato, and Gian Cesare Guidi
Blood Coagulation & Fibrinolysis, 2007, Volume 18, Number 5, Page 525

Comments (0)

Please log in or register to comment.