Jump to ContentJump to Main Navigation
Show Summary Details

Clinical Chemistry and Laboratory Medicine (CCLM)

Published in Association with the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM)

Editor-in-Chief: Plebani, Mario

Ed. by Gillery, Philippe / Lackner, Karl J. / Lippi, Giuseppe / Melichar, Bohuslav / Payne, Deborah A. / Schlattmann, Peter / Tate, Jillian R.

IMPACT FACTOR increased in 2015: 3.017
Rank 5 out of 30 in category Medical Laboratory Technology in the 2014 Thomson Reuters Journal Citation Report/Science Edition

SCImago Journal Rank (SJR) 2015: 0.873
Source Normalized Impact per Paper (SNIP) 2015: 0.982
Impact per Publication (IPP) 2015: 2.238

249,00 € / $374.00 / £187.00*

See all formats and pricing


Select Volume and Issue


30,00 € / $42.00 / £23.00

Get Access to Full Text

Interpretation of serum parathyroid hormone concentrations in dialysis patients: what do the KDIGO guidelines change for the clinical laboratory?

Jean-Claude Souberbielle1 / Etienne Cavalier2 / Guillaume Jean3

1Laboratoire d'Explorations Fonctionnelles, Hôpital Necker-Enfants Malades, Paris, France and Université Paris Descartes, INSERM U845, Paris, France

2Department of Clinical Chemistry, University of Liège, University Hospital of Liège, Liège, Belgium

3Centre de Rein Artificiel, Tassin la Demi-lune, France

Corresponding author: Jean-Claude Souberbielle, Laboratoire d'Explorations Fonctionnelles, Hôpital Necker-Enfants Malades, 149 rue de Sèvres, 75015, Paris, France and Université Paris Descartes, INSERM U845, Paris, France

Citation Information: Clinical Chemistry and Laboratory Medicine. Volume 48, Issue 6, Pages 769–774, ISSN (Online) 1437-4331, ISSN (Print) 1434-6621, DOI: 10.1515/CCLM.2010.157, March 2010

Publication History

Published Online:


The Kidney Disease: Improving Global Outcomes (KDIGO) have recently replaced the K/DOQI guidelines to help nephrologists in diagnosing, treating and monitoring chronic kidney disease mineral and bone disorders (CKD-MBD). Here, we comment on the KDIGO recommendations concerning the interpretation of parathyroid hormone (PTH) concentrations in dialysis patients: “In patients with CKD stage 5D, we suggest maintaining iPTH in the range of approximately two to nine times the upper normal limit of the assay. We suggest that marked changes in PTH concentrations in either direction within this range prompt an initiation or change in therapy to avoid progression to concentrations outside of this range”. Our comments concern the interpretation of PTH in dialysis patients, but also the more global problem of establishing normal values for PTH.

Clin Chem Lab Med 2010;48:769–74.

Keywords: chronic kidney disease; clinical guidelines; dialysis; parathyroid hormone; reference values

Citing Articles

Here you can find all Crossref-listed publications in which this article is cited. If you would like to receive automatic email messages as soon as this article is cited in other publications, simply activate the “Citation Alert” on the top of this page.

Julia B. Lewis
Seminars in Dialysis, 2015, Page n/a
Said Kamel, Tilman Drueke, and Ziad Massy
Revue Francophone des Laboratoires, 2013, Volume 2013, Number 455, Page 29
Paulina Salas, Viola Pinto, Josefina Rodriguez, Maria Jose Zambrano, and Veronica Mericq
International Journal of Endocrinology, 2013, Volume 2013, Page 1
C. M. Sturgeon, S. M. Sprague, and W. Metcalfe
Nephrology Dialysis Transplantation, 2011, Volume 26, Number 11, Page 3440
Luca Giovanella
La Rivista Italiana della Medicina di Laboratorio - Italian Journal of Laboratory Medicine, 2011, Volume 7, Number 3, Page 140
Guillaume Jean
La Presse Médicale, 2011, Volume 40, Number 11, Page 1043
Guillaume Jean and Charles Chazot
Néphrologie & Thérapeutique, 2012, Volume 8, Number 3, Page 131
D. J. A. Goldsmith, A. Covic, D. Fouque, F. Locatelli, K. Olgaard, M. Rodriguez, G. Spasovski, P. Urena, C. Zoccali, G. M. London, and R. Vanholder
Nephrology Dialysis Transplantation, 2010, Volume 25, Number 12, Page 3823

Comments (0)

Please log in or register to comment.