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Clinical Chemistry and Laboratory Medicine (CCLM)

Published in Association with the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM)

Editor-in-Chief: Plebani, Mario

Ed. by Gillery, Philippe / Lackner, Karl J. / Lippi, Giuseppe / Melichar, Bohuslav / Payne, Deborah A. / Schlattmann, Peter / Tate, Jillian R.

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Volume 49, Issue 8 (Aug 2011)


New biomarkers for acute renal injury

Sachin S. Soni
  • Manik Hospital and Research Centre, Aurangabad, India
  • Assistant Professor in Nephrology, MGM Medical College, Aurangabad, India
  • Other articles by this author:
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/ Rupesh Pophale / Claudio Ronco
  • Department of Nephrology, Dialysis and Transplantation, International Renal Research Institute, Vicenza (IRRIV), Italy
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  • Other articles by this author:
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Published Online: 2011-07-05 | DOI: https://doi.org/10.1515/CCLM.2011.664


Incidence of acute kidney injury (AKI) is increasing rapidly to epidemic proportions. Development of AKI, especially in intensive care settings, is associated with increased morbidity, mortality and hospitalization costs. Currently available diagnostic tools are mostly insensitive for early diagnosis, however prompt diagnosis and risk stratification are necessary for guiding therapy and preventing progression of disease. Finding an early, reliable, suitable, easily reproducible, economical and accurate biomarker for AKI is a top research priority. In recent years, many urinary and serum proteins have been investigated as possible early markers of AKI and some of them have shown great promise. This topic reviews some of the emerging biomarkers of AKI.

About the article

Corresponding author: Claudio Ronco, MD, Director, Department of Nephrology Dialysis and Transplantation, International Renal Research Institute Vicenza (IRRIV), San Bortolo Hospital, Viale Rodolfi, 37, 36100 Vicenza, Italy Phone: +39 0444 753869, Fax: +39 0444 753949

Received: 2011-03-31

Accepted: 2011-06-08

Published Online: 2011-07-05

Published in Print: 2011-08-01

Citation Information: Clinical Chemistry and Laboratory Medicine, ISSN (Online) 1437-4331, ISSN (Print) 1434-6621, DOI: https://doi.org/10.1515/CCLM.2011.664.

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©2011 by Walter de Gruyter Berlin Boston. Copyright Clearance Center

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