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Clinical Chemistry and Laboratory Medicine (CCLM)

Published in Association with the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM)

Editor-in-Chief: Plebani, Mario

Ed. by Gillery, Philippe / Lackner, Karl J. / Lippi, Giuseppe / Melichar, Bohuslav / Payne, Deborah A. / Schlattmann, Peter / Tate, Jillian R.

12 Issues per year


IMPACT FACTOR 2017: 3.556

CiteScore 2017: 2.34

SCImago Journal Rank (SJR) 2017: 1.114
Source Normalized Impact per Paper (SNIP) 2017: 1.188

Online
ISSN
1437-4331
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Volume 51, Issue 9

Issues

Falsely elevated cobalamin concentration in multiple assays in a patient with pernicious anemia: a case study

André P. van Rossum
  • Corresponding author
  • Department of Clinical Chemistry and Hematology, Bronovo Hospital, Bronovolaan The Hague, The Netherlands
  • Email
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ L. Thomas Vlasveld / Ad Castel
  • Department of Clinical Chemistry and Hematology, Bronovo Hospital, Bronovolaan The Hague, The Netherlands
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
Published Online: 2013-05-14 | DOI: https://doi.org/10.1515/cclm-2013-0131

References

  • 1.

    Yang DT, Cook RF. Spuriously elevations of vitamin B12 with pernicious anemia. N Engl J Med 2012;366:1742–3.CrossrefGoogle Scholar

  • 2.

    Vlasveld LT, van’t Wout JW, Meeuwissen P, Castel A. High measured cobalamin (vitamin B12) concentration attributable to an analytical problem in testing serum from a patient with pernicious anemia. Clin Chem 2006;52:157–8.CrossrefGoogle Scholar

  • 3.

    Maugh K. High measured cobalamin (vitamin B12) concentration attributable to an analytical problem in testing serum from a patient with pernicious anemia: reply. Clin Chem 2006;52:158–9.CrossrefGoogle Scholar

  • 4.

    Carmel R, Brar S, Agrawal A, Penha PD. Failure of assay to identify low cobalamin concentrations. Clin Chem 2000;46:2017–8.Google Scholar

  • 5.

    Carmel R, Agrawal YP. Failures of cobalamin assays in pernicious anemia. N Engl J Med 2012;367:385–6.Google Scholar

  • 6.

    Heil SG, de Jonge R, de Rotte MC, van Wijnen M, Heiner-Fokkema RM, Kobold AC, et al. Screening for metabolic vitamin B12 deficiency by holotranscobalamin in patients suspected of vitamin B12 deficiency: a multicentric study. Ann Clin Biochem 2012;49:184–9.CrossrefWeb of ScienceGoogle Scholar

About the article

Corresponding author: André P. van Rossum, Department of Clinical Chemistry and Hematology, Bronovo Hospital, Bronovolaan 5 2597 AX The Hague, The Netherlands


Received: 2013-02-19

Accepted: 2013-04-16

Published Online: 2013-05-14

Published in Print: 2013-09-01


Citation Information: Clinical Chemistry and Laboratory Medicine, Volume 51, Issue 9, Pages e217–e219, ISSN (Online) 1437-4331, ISSN (Print) 1434-6621, DOI: https://doi.org/10.1515/cclm-2013-0131.

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