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Clinical Chemistry and Laboratory Medicine (CCLM)

Published in Association with the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM)

Editor-in-Chief: Plebani, Mario

Ed. by Gillery, Philippe / Greaves, Ronda / Lackner, Karl J. / Lippi, Giuseppe / Melichar, Bohuslav / Payne, Deborah A. / Schlattmann, Peter


IMPACT FACTOR 2018: 3.638

CiteScore 2018: 2.44

SCImago Journal Rank (SJR) 2018: 1.191
Source Normalized Impact per Paper (SNIP) 2018: 1.205

Online
ISSN
1437-4331
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Volume 55, Issue 2

Issues

How can we evaluate differences between serial measurements on the same sample? A new approach based on within-subject biological variation

Abdurrahman Coskun
  • Corresponding author
  • Acibadem University, School of Medicine, Department of Medical Biochemistry, Istanbul, Turkey
  • Acibadem Labmed Clinical Laboratories, Istanbul, Turkey
  • Email
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Mustafa Serteser
  • Acibadem University, School of Medicine, Department of Medical Biochemistry, Istanbul, Turkey
  • Acibadem Labmed Clinical Laboratories, Istanbul, Turkey
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Hande F. Karpuzoglu / Ibrahim Unsal
  • Acibadem University, School of Medicine, Department of Medical Biochemistry, Istanbul, Turkey
  • Acibadem Labmed Clinical Laboratories, Istanbul, Turkey
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
Published Online: 2016-08-09 | DOI: https://doi.org/10.1515/cclm-2016-0574

References

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    Dawson B, Trapp RG. Basic and clinical biostatistics, 4th ed. New York: Lange Medical Books/McGraw-Hill, 2004.Google Scholar

  • 2.

    Fraser CG. Biological variation: from principles to practice. Washington, DC: AACC Press, 2001.Google Scholar

  • 3.

    Sandberg S, Fraser CG, Horvath AR, Jansen R, Jones G, Oosterhuis W, et al. Defining analytical performance specifications: Consensus statement from the 1st Strategic Conference of the European Federation of Clinical Chemistry and Laboratory Medicine. Clin Chem Lab Med 2015;53:833–5.Google Scholar

  • 4.

    https://www.westgard.com/biodatabase1.htm. Accessed June 2016.

  • 5.

    Petersen PH, Fraser CG, Westgard JO, Larsen ML. Analytical goal-setting for monitoring patients when two analytical methods are used. Clin Chem 1992;38:2256–60.Google Scholar

About the article

Corresponding author: Abdurrahman Coskun, MD, Acibadem University, School of Medicine, Department of Medical Biochemistry, Istanbul, Turkey


Received: 2016-06-28

Accepted: 2016-07-07

Published Online: 2016-08-09

Published in Print: 2017-02-01


Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.

Research funding: None declared.

Employment or leadership: None declared.

Honorarium: None declared.

Competing interests: The funding organization(s) played no role in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the report for publication.


Citation Information: Clinical Chemistry and Laboratory Medicine (CCLM), Volume 55, Issue 2, Pages e44–e46, ISSN (Online) 1437-4331, ISSN (Print) 1434-6621, DOI: https://doi.org/10.1515/cclm-2016-0574.

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