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Clinical Chemistry and Laboratory Medicine (CCLM)

Published in Association with the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM)

Editor-in-Chief: Plebani, Mario

Ed. by Gillery, Philippe / Lackner, Karl J. / Lippi, Giuseppe / Melichar, Bohuslav / Payne, Deborah A. / Schlattmann, Peter / Tate, Jillian R.

12 Issues per year


IMPACT FACTOR 2017: 3.556

CiteScore 2017: 2.34

SCImago Journal Rank (SJR) 2017: 1.114
Source Normalized Impact per Paper (SNIP) 2017: 1.188

Online
ISSN
1437-4331
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Volume 56, Issue 6

Issues

Falsely elevated plasma testosterone concentrations in neonates: importance of LC-MS/MS measurements

Henrike M. Hamer / Martijn J.J. Finken
  • Department of Pediatric Endocrinology, VU University Medical Center, Amsterdam, The Netherlands
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Antonius E. van Herwaarden
  • Department of Laboratory Medicine, Radboud University Medical Center, Geert Grooteplein 10, 6525 GA Nijmegen, The Netherlands
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Therina du Toit / Amanda C. Swart / Annemieke C. Heijboer
Published Online: 2018-01-08 | DOI: https://doi.org/10.1515/cclm-2017-1028

References

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    Groenestege WM, Bui HN, ten Kate J, Menheere PP, Oosterhuis WP, Vader HL, et al. Accuracy of first and second generation testosterone assays and improvement through sample extraction. Clin Chem 2012;58:1154–6.CrossrefWeb of SciencePubMedGoogle Scholar

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    Kulle A, Krone N, Holterhus PM, Schuler G, Greaves RF, Juul A, et al. Steroid hormone analysis in diagnosis and treatment of DSD: position paper of EU COST Action BM 1303 ‘DSDnet’. Eur J Endocrinol 2017;176:P1–9.PubMedCrossrefGoogle Scholar

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    Bui HN, Sluss PM, Blincko S, Knol DL, Blankenstein MA, Heijboer AC. Dynamics of serum testosterone during the menstrual cycle evaluated by daily measurements with an ID-LC-MS/MS method and a 2nd generation automated immunoassay. Steroids 2013;78:96–101.Web of ScienceCrossrefGoogle Scholar

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    Owen WE, Rawlins ML, Roberts WL. Selected performance characteristics of the Roche Elecsys testosterone II assay on the Modular analytics E 170 analyzer. Clin Chim Acta 2010;411:1073–9.Web of ScienceCrossrefPubMedGoogle Scholar

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    du Toit T, Bloem LM, Quanson JL, Ehlers R, Serafin AM, Swart AC. Profiling adrenal 11beta-hydroxyandrostenedione metabolites in prostate cancer cells, tissue and plasma: UPC2-MS/MS quantification of 11beta-hydroxytestosterone, 11keto-testosterone and 11keto-dihydrotestosterone. J Steroid Biochem Mol Biol 2017;166:54–67.PubMedCrossrefGoogle Scholar

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    Winter JS, Hughes IA, Reyes FI, Faiman C. Pituitary-gonadal relations in infancy: 2. Patterns of serum gonadal steroid concentrations in man from birth to two years of age. J Clin Endocrinol Metab 1976;42:679–86.CrossrefPubMedGoogle Scholar

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    Forest MG, Sizonenko PC, Cathiard AM, Bertrand J. Hypophyso-gonadal function in humans during the first year of life. 1. Evidence for testicular activity in early infancy. J Clin Invest 1974;53:819–28.CrossrefPubMedGoogle Scholar

About the article

Corresponding author: Dr. Annemieke C. Heijboer, Department of Clinical Chemistry, VU Medical Centre, PO box 7057, 1007 MB Amsterdam, The Netherlands, Phone: 0031(0)20-4442640, Fax: 0031(0)20-4443895


Received: 2017-11-08

Accepted: 2017-12-11

Published Online: 2018-01-08

Published in Print: 2018-05-24


Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.

Research funding: None declared.

Employment or leadership: None declared.

Honorarium: None declared.

Competing interests: The funding organization(s) played no role in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the report for publication.


Citation Information: Clinical Chemistry and Laboratory Medicine (CCLM), Volume 56, Issue 6, Pages e141–e143, ISSN (Online) 1437-4331, ISSN (Print) 1434-6621, DOI: https://doi.org/10.1515/cclm-2017-1028.

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