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Clinical Chemistry and Laboratory Medicine (CCLM)

Published in Association with the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM)

Editor-in-Chief: Plebani, Mario

Ed. by Gillery, Philippe / Greaves, Ronda / Lackner, Karl J. / Lippi, Giuseppe / Melichar, Bohuslav / Payne, Deborah A. / Schlattmann, Peter


IMPACT FACTOR 2018: 3.638

CiteScore 2018: 2.44

SCImago Journal Rank (SJR) 2018: 1.191
Source Normalized Impact per Paper (SNIP) 2018: 1.205

Online
ISSN
1437-4331
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Volume 57, Issue 12

Issues

Detection of a novel hemoglobin variant Hb Liaoning by matrix assisted laser desorption/ionization-time of flight mass spectrometry

Anping Xu
  • Department of Laboratory Medicine, Peking University Shenzhen Hospital, Shenzhen, Guangdong, P.R. China
  • Other articles by this author:
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/ Yajun Wang / Weidong Chen
  • Department of Laboratory Medicine, Peking University Shenzhen Hospital, Shenzhen, Guangdong, P.R. China
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/ Guiping Liu
  • Department of Laboratory Medicine, Peking University Shenzhen Hospital, Shenzhen, Guangdong, P.R. China
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/ Xiaofeng Li
  • Department of Laboratory Medicine, Peking University Shenzhen Hospital, Shenzhen, Guangdong, P.R. China
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/ Jie Li
  • Corresponding author
  • Department of Laboratory Medicine, Peking University Shenzhen Hospital, Lianhua Road No. 1120, Futian District, Shenzhen, Guangdong, P.R. China, Phone: +86-0755-83923333-2295
  • Email
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/ Ling Ji
  • Corresponding author
  • Department of Laboratory Medicine, Peking University Shenzhen Hospital, Lianhua Road No. 1120, Futian District, Shenzhen, Guangdong, P.R. China, Phone: +86-0755-83923333-2299
  • Email
  • Other articles by this author:
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Published Online: 2019-06-27 | DOI: https://doi.org/10.1515/cclm-2019-0300

References

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    HbVar. A database of human hemoglobin variants and thalassemias. http://globin.bx.psu.edu/cgi-bin/hbvar/counter. Accessed: 25 Feb 2018.

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    Wild BJ, Bain BJ. Detection and quantitation of normal and variant haemoglobins: an analytical review. Ann Clin Biochem 2004;41:355–69.PubMedCrossrefGoogle Scholar

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    Wild BJ, Green BN, Cooper EK, Lalloz MR, Erten S, Stephens AD, et al. Rapid identification of hemoglobin variants by electrospray ionization mass spectrometry. Blood Cells Mol Dis 2001;27:691–704.CrossrefPubMedGoogle Scholar

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    Basilico F, Di Silvestre D, Sedini S, Petretto A, Levreri I, Melioli G, et al. New approach for rapid detection of known hemoglobin variants using LC-MS/MS combined with a peptide database. J Mass Spectrom 2007;42:288–92.CrossrefPubMedWeb of ScienceGoogle Scholar

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    Kleinert P, Schmid M, Zurbriggen K, Speer O, SchmuggeM, Roschitzki B, et al. Mass spectrometry: a tool for enhanced detection of hemoglobin variants. Clin Chem 2008;54:69–76.Web of SciencePubMedGoogle Scholar

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    Jaisson S, Leroy N, Meurice J, Guillard E, Gillery P. First evaluation of Capillarys 2 Flex Piercing® (Sebia) as a new analyzer for HbA1c assay by capillary electrophoresis. Clin Chem Lab Med 2012;50:1769–75.PubMedGoogle Scholar

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    http://www.ngsp.org/news.asp. Accessed: 25 Feb 2018.

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    Little RR, Vesper H, Rohlfing CL, Ospina M, Safar-Pour S, Roberts WL. Validation by a mass spectrometric reference method of use of boronate affinity chromatography to measure glycohemoglobin in the presence of hemoglobin S and C traits. Clin Chem 2005;51:264–5.Google Scholar

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    Biroccio A, Urbani A, Massoud R, di Ilio C, Sacchetta P, Bernardini S, et al. A quantitative method for the analysis of glycated and glutathionylated hemoglobin by matrix-assisted laser desorption ionization-time of flight mass spectrometry. Anal Biochem 2005;336:279–88.PubMedCrossrefGoogle Scholar

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    Hattan SJ, Parker KC, Vestal ML, Yang JY, Herold DA, DuncanMW. Analysis and quantitation of glycated hemoglobin by matrix assisted laser desorption/ionization time of flight mass spectrometry. J Am Soc Mass Spectrom 2016;27:532–41.Web of ScienceCrossrefPubMedGoogle Scholar

About the article

Received: 2019-03-19

Accepted: 2019-05-23

Published Online: 2019-06-27

Published in Print: 2019-11-26


Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.

Research funding: This study was supported by Research Foundation of Peking University Shenzhen Hospital (JCYJ2018003, JCYJ2018005).

Employment or leadership: None declared.

Honorarium: None declared.

Competing interests: The funding organization(s) played no role in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the report for publication.


Citation Information: Clinical Chemistry and Laboratory Medicine (CCLM), Volume 57, Issue 12, Pages e328–e330, ISSN (Online) 1437-4331, ISSN (Print) 1434-6621, DOI: https://doi.org/10.1515/cclm-2019-0300.

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