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Clinical Chemistry and Laboratory Medicine (CCLM)

Published in Association with the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM)

Editor-in-Chief: Plebani, Mario

Ed. by Gillery, Philippe / Greaves, Ronda / Lackner, Karl J. / Lippi, Giuseppe / Melichar, Bohuslav / Payne, Deborah A. / Schlattmann, Peter


IMPACT FACTOR 2018: 3.638

CiteScore 2018: 2.44

SCImago Journal Rank (SJR) 2018: 1.191
Source Normalized Impact per Paper (SNIP) 2018: 1.205

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Volume 57, Issue 6

Issues

Suppressing all test results in grossly hemolyzed samples: is this approach appropriate in every case?

Dominika Szoke
  • Corresponding author
  • UOC Patologia Clinica, ASST Fatebenefratelli-Sacco, Via GB Grassi 74, 20157 Milano, Italia, Phone: +39 02 3904 2683, Fax: +39 02 3904 2364
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  • Other articles by this author:
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/ Simone Caruso / Sara Pasqualetti / Elena Aloisio / Felicia Stefania Falvella / Alberto Dolci / Mauro Panteghini
Published Online: 2018-10-23 | DOI: https://doi.org/10.1515/cclm-2018-1071

References

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    Lippi G, Cadamuro J, von Meyer A, Simundic AM, on behalf of the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Working Group for Preanalytical Phase (WG-PRE). Practical recommendations for managing hemolyzed samples in clinical chemistry testing. Clin Chem Lab Med 2018;56:718–27.CrossrefWeb of SciencePubMedGoogle Scholar

  • 2.

    Lippi G, Blanckaert N, Bonini P, Green S, Kitchen S, Palicka V, et al. Haemolysis: an overview of the leading cause of unsuitable specimens in clinical laboratories. Clin Chem Lab Med 2008;46:764–72.PubMedWeb of ScienceGoogle Scholar

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    Barcellini W, Fattizzo B. Clinical applications of hemolytic markers in the differential diagnosis and management of hemolytic anemia. Dis Markers 2015;2015:635670.PubMedWeb of ScienceGoogle Scholar

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    Carraro P, Servidio G, Plebani M. Hemolyzed specimens: a reason for rejection or a clinical challenge? Clin Chem 2000;46:306–7.Google Scholar

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    Dolci A, Panteghini M. Harmonization of automated hemolysis index assessment and use: is it possible? Clin Chim Acta 2014;432:38–43.Web of SciencePubMedCrossrefGoogle Scholar

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    Dolci A, Giavarina D, Pasqualetti S, Szőke D, Panteghini M. Total laboratory automation: do stat tests still matter? Clin Biochem 2017;50:605–11.Web of ScienceCrossrefPubMedGoogle Scholar

  • 7.

    Aloisio E, Carnevale A, Pasqualetti S, Birindelli S, Dolci A, Panteghini M. Random uncertainty of photometric determination of hemolysis index on the Abbott Architect c16000 platform. Clin Biochem 2018;57:62–4.Web of ScienceCrossrefPubMedGoogle Scholar

  • 8.

    Pasqualetti S, Szőke D, Panteghini M. Heparinate but not serum tubes are susceptible to hemolysis by pneumatic tube transportation. Clin Chem Lab Med 2016;54:785–9.PubMedWeb of ScienceGoogle Scholar

  • 9.

    Clinical and Laboratory Standards Institute [CLSI]. Hemolysis, icterus, and lipemia/turbidity indices as indicators of interference in clinical laboratory analysis: approved guideline. CLSI document C56-A. Wayne, PA: Clinical and Laboratory Standards Institute, 2012.Google Scholar

  • 10.

    Cadamuro J, Mrazek C, Haschke-Becher E, Sandberg S. To report or not to report: a proposal on how to deal with altered test results in hemolytic samples. Clin Chem Lab Med 2017;55:1109–11.Web of SciencePubMedCrossrefGoogle Scholar

About the article

Received: 2018-10-01

Accepted: 2018-10-02

Published Online: 2018-10-23

Published in Print: 2019-05-27


Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.

Research funding: None declared.

Employment or leadership: None declared.

Honorarium: None declared.

Competing interests: The funding organization(s) played no role in the study design; in the collection, analysis and interpretation of data; in the writing of the report; or in the decision to submit the report for publication.


Citation Information: Clinical Chemistry and Laboratory Medicine (CCLM), Volume 57, Issue 6, Pages e118–e120, ISSN (Online) 1437-4331, ISSN (Print) 1434-6621, DOI: https://doi.org/10.1515/cclm-2018-1071.

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