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Clinical Chemistry and Laboratory Medicine (CCLM)

Published in Association with the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM)

Editor-in-Chief: Plebani, Mario

Ed. by Gillery, Philippe / Greaves, Ronda / Lackner, Karl J. / Lippi, Giuseppe / Melichar, Bohuslav / Payne, Deborah A. / Schlattmann, Peter

IMPACT FACTOR 2018: 3.638

CiteScore 2018: 2.44

SCImago Journal Rank (SJR) 2018: 1.191
Source Normalized Impact per Paper (SNIP) 2018: 1.205

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Reflex TSH strategy: the good, the bad and the ugly

Mario PlebaniORCID iD: https://orcid.org/0000-0002-0270-1711 / Luca Giovanella
  • Clinic for Nuclear Medicine and Competence Centre for Thyroid Diseases, Ente Ospedaliero Cantonale, Bellinzona, Switzerland
  • Clinic for Nuclear Medicine, University Hospital and University of Zurich, Zurich, Switzerland
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
Published Online: 2019-07-17 | DOI: https://doi.org/10.1515/cclm-2019-0625


  • 1.

    Koulouri O, Moran C, Halsall D, Chatterjee K, Gurnell M. Pitfalls in the measurement and interpretation of thyroid function tests. Best Pract Res Clin Endocrinol Metab 2013;27:745–62.PubMedCrossrefGoogle Scholar

  • 2.

    Jonklaas J, Bianco AC, Bauer AJ, Burman KD, Cappola AR, Celi FS, et al. Guidelines for the treatment of hypothyroidism: prepared by the American Thyroid Association Task Force on Thyroid Hormone Replacement. Thyroid 2014;24:1670–751.CrossrefPubMedWeb of ScienceGoogle Scholar

  • 3.

    Garber J, Cobin R, Gharib H, Hennessey J, Klein I, Mechanick J, et al. Clinical practice guidelines for hypothyroidism in adults: cosponsored by the American Association of Clinical Endocrinologists and the American Thyroid Association. Endocr Pract 2012;18:988–1028.Web of ScienceCrossrefGoogle Scholar

  • 4.

    Demers LM, Spencer CA. Laboratory medicine practice guidelines: laboratory support for the diagnosis and monitoring of thyroid disease. Clin Endocrinol 2003;58:138–40.CrossrefGoogle Scholar

  • 5.

    Henze M, Brown SJ, Hadlow NC, Walsh JP. Rationalizing thyroid function testing: which TSH cutoffs are optimal for testing free T4? J Clin Endocrinol Metab 2017;102:4235–41.PubMedWeb of ScienceCrossrefGoogle Scholar

  • 6.

    Taher J, Brinc D, Gilmour J, Beriault D. Validating thyroid stimulating hormone (TSH) reflexive testing cutpoints in a tertiary care institution. Clin Chem Lab Med 2019;In press.Google Scholar

  • 7.

    Gill J, Barakauskas VE, Thomas D, Rodriguez-Capote K, Higgins T, Zhang D, et al. Evaluation of thyroid test utilization through analysis of population-level data. Clin Chem Lab Med 2017;55:1898–906.PubMedWeb of ScienceGoogle Scholar

  • 8.

    Beck-Peccoz P, Rodari G, Giavoli C, Lania A. Central hypothyroidism – a neglected thyroid disorder. Nat Rev Endocrinol 2017;13:588–98.Web of SciencePubMedCrossrefGoogle Scholar

  • 9.

    Kahapola-Arachchige KM, Hadlow N, Wardrop R, Lim EM, Walsh JP. Age-specific TSH reference ranges have minimal impact on the diagnosis of thyroid dysfunction. Clin Endocrinol 2012;77:773–9.Web of ScienceCrossrefGoogle Scholar

About the article

Published Online: 2019-07-17

Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.

Research funding: None declared.

Employment or leadership: None declared.

Honorarium: None declared.

Citation Information: Clinical Chemistry and Laboratory Medicine (CCLM), 20190625, ISSN (Online) 1437-4331, ISSN (Print) 1434-6621, DOI: https://doi.org/10.1515/cclm-2019-0625.

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