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Current Directions in Biomedical Engineering

Joint Journal of the German Society for Biomedical Engineering in VDE and the Austrian and Swiss Societies for Biomedical Engineering

Editor-in-Chief: Dössel, Olaf

Editorial Board: Augat, Peter / Buzug, Thorsten M. / Haueisen, Jens / Jockenhoevel, Stefan / Knaup-Gregori, Petra / Kraft, Marc / Lenarz, Thomas / Leonhardt, Steffen / Malberg, Hagen / Penzel, Thomas / Plank, Gernot / Radermacher, Klaus M. / Schkommodau, Erik / Stieglitz, Thomas / Urban, Gerald A.


CiteScore 2018: 0.47

Source Normalized Impact per Paper (SNIP) 2018: 0.377

Open Access
Online
ISSN
2364-5504
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Tissue-specific transformation model for CT-images

Implementation of a volume-calculation on voxel-level

Kathrin Bartelheimer
  • Corresponding author
  • Division of Medical Physics in Radiation Oncology, German Cancer Research Center (DKFZ) Heidelberg, National Center for Radiation Research in Oncology (NCRO), Heidelberg Institute for Radiation Oncology (HIRO), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
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  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Hendrik Teske
  • Division of Medical Physics in Radiation Oncology, German Cancer Research Center (DKFZ) Heidelberg, National Center for Radiation Research in Oncology (NCRO), Heidelberg Institute for Radiation Oncology (HIRO), Germany
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Rolf Bendl
  • Division of Medical Physics in Radiation Oncology, German Cancer Research Center (DKFZ) Heidelberg, Heilbronn University, Faculty of Computer Science, Germany
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  • De Gruyter OnlineGoogle Scholar
/ Kristina Giske
  • Division of Medical Physics in Radiation Oncology, German Cancer Research Center (DKFZ) Heidelberg, National Center for Radiation Research in Oncology (NCRO), Heidelberg Institute for Radiation Oncology (HIRO), Germany
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
Published Online: 2017-09-07 | DOI: https://doi.org/10.1515/cdbme-2017-0111

Abstract

During radiotherapy, posture changes and volume changing deformations like growing or shrinking tissue result in anatomical deformations. The basis for investigating the impact of such deformations on dose uncertainties, are model-based tools for deformation analysis. In this context, we propose a transformation model based on the information of CT-images, which allows an on-the-fly calculation of voxel volumes. Our model is based on the concept of the chainmail algorithm and describes deformation on voxel-level. With an exemplary input of a set of landmark pairs, generated by a kinematic head-and-neck skeleton model, CT-images (512x512x126 voxel) can be deformed with an on-the-fly volume calculation in less than 70s. The volume calculation delivers insight into model-characteristic volume changes and is a prerequisite for implementing tissue growth and shrinkage.

Keywords: soft tissue deformation; volume changing deformations; transformation mode; chainmail algorithm

About the article

Published Online: 2017-09-07


Citation Information: Current Directions in Biomedical Engineering, Volume 3, Issue 2, Pages 525–528, ISSN (Online) 2364-5504, DOI: https://doi.org/10.1515/cdbme-2017-0111.

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©2017 Kathrin Bartelheimer et al., published by De Gruyter. This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License. BY-NC-ND 4.0

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