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Current Directions in Biomedical Engineering

Joint Journal of the German Society for Biomedical Engineering in VDE and the Austrian and Swiss Societies for Biomedical Engineering

Editor-in-Chief: Dössel, Olaf

Editorial Board: Augat, Peter / Buzug, Thorsten M. / Haueisen, Jens / Jockenhoevel, Stefan / Knaup-Gregori, Petra / Kraft, Marc / Lenarz, Thomas / Leonhardt, Steffen / Malberg, Hagen / Penzel, Thomas / Plank, Gernot / Radermacher, Klaus M. / Schkommodau, Erik / Stieglitz, Thomas / Urban, Gerald A.


CiteScore 2018: 0.47

Source Normalized Impact per Paper (SNIP) 2018: 0.377

Open Access
Online
ISSN
2364-5504
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Electrical stimulation with motility analysis of five parts of the gastrointestinal tract

First evaluation of an experimental protocol in a porcine model

Jonas F. Schiemer
  • Department of General, Visceral and Transplant Surgery, University Medicine of the Johannes Gutenberg-University, Mainz, Germany
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/ Axel Heimann
  • Institute for Neurosurgical Pathophysiology, University Medicine of the Johannes Gutenberg-University, Mainz, Germany
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/ Karin Somerlik-Fuchs / Roman Ruff
  • Department of Biomedical Engineering, Fraunhofer Institute for Biomedical Engineering, St. Ingbert, Germany
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/ Klaus-Peter Hoffmann
  • Department of Biomedical Engineering, Fraunhofer Institute for Biomedical Engineering, St. Ingbert, Germany
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/ Jan Baumgart
  • Translational Animal Research Center, University Medicine of the Johannes Gutenberg-University, Mainz, Germany
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/ Werner Kneist
  • Corresponding author
  • Department of General, Visceral and Transplant Surgery, University Medicine of the Johannes Gutenberg-University, Mainz, Germany
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Published Online: 2018-09-22 | DOI: https://doi.org/10.1515/cdbme-2018-0003

Abstract

Gastrointestinal (GI) motility disorders are frequent and clinically significant conditions with impairment of patient’s quality of life. Examples range from upper GI symptoms such as dysphagia and gastroparesis to lower GI manifestations, namely chronic-intestinal pseudo obstruction, diarrhea and constipation. Furthermore, postoperative motility disorders are common. Currently, available pharmacological or dietetic treatment options are limited. Since GI motility is based on myoelectric activity, electrical stimulation (ES) is a promising alternative. Numerous studies have demonstrated suitable pacing strategies and parameters in different GI segments. However, results of multilocular ES are rare. We report the first experimental study to evaluate ES of five GI parts in a porcine model. Multi-channel electromyography (EMG) recordings of gastrointestinal baseline and poststimulatory electrical activity were realized together with video-based marker tracking (VBMT). ES provoked visible GI contractions and appeared to modulate frequencies of slow waves and spikes. Further investigations are needed for analysis of locoregional and cross-organ effects of ES on the GI tract.

Keywords: Gastrointestinal motility; Motility disorders; Electromyography; Video analysis; Electrical stimulation

About the article

Published Online: 2018-09-22

Published in Print: 2018-09-01


Citation Information: Current Directions in Biomedical Engineering, Volume 4, Issue 1, Pages 9–11, ISSN (Online) 2364-5504, DOI: https://doi.org/10.1515/cdbme-2018-0003.

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[1]
Jonas F Schiemer, Axel Heimann, Karin H Somerlik-Fuchs, Roman Ruff, Klaus-Peter Hoffmann, Jan Baumgart, Manfred Berres, Hauke Lang, and Werner Kneist
Journal of Neurogastroenterology and Motility, 2019, Volume 25, Number 3, Page 461

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