Jump to ContentJump to Main Navigation
Show Summary Details
More options …

Current Directions in Biomedical Engineering

Joint Journal of the German Society for Biomedical Engineering in VDE and the Austrian and Swiss Societies for Biomedical Engineering

Editor-in-Chief: Dössel, Olaf

Editorial Board: Augat, Peter / Buzug, Thorsten M. / Haueisen, Jens / Jockenhoevel, Stefan / Knaup-Gregori, Petra / Kraft, Marc / Lenarz, Thomas / Leonhardt, Steffen / Malberg, Hagen / Penzel, Thomas / Plank, Gernot / Radermacher, Klaus M. / Schkommodau, Erik / Stieglitz, Thomas / Urban, Gerald A.


CiteScore 2018: 0.47

Source Normalized Impact per Paper (SNIP) 2018: 0.377

Open Access
Online
ISSN
2364-5504
See all formats and pricing
More options …

Application of thermography for cerebral perfusion imaging during aneurysm surgery

Juliane Müller
  • Corresponding author
  • TU Dresden, Faculty of Medicine Carl Gustav Carus, Anesthesiology and Intensive Care Medicine, Clinical Sensoring and Monitoring, Fetscherstraße 74, 01307 Dresden, Germany
  • Email
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Valentin Schreiter / Elisa Böhl / Gerald Steiner
  • TU Dresden, Faculty of Medicine Carl Gustav Carus, Anesthesiology and Intensive Care Medicine, Clinical Sensoring and Monitoring, Dresden, Germany
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Edmund Koch
  • TU Dresden, Faculty of Medicine Carl Gustav Carus, Anesthesiology and Intensive Care Medicine, Clinical Sensoring and Monitoring, Dresden, Germany
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Gabriele Schackert / Matthias Kirsch
Published Online: 2018-09-22 | DOI: https://doi.org/10.1515/cdbme-2018-0008

Abstract

The success of aneurysm surgery depends on complete clipping of the aneurysmal sacculation without compromising quality of cerebral perfusion of vessels concerned. An established intraoperative method to visualize cerebral blood flow i n a pparent v essels i s fl uorescence vi deo angiography based on indocyanine green (ICG). However, major disadvantages of indocyanine green video angiography (ICG VA) are the need of a specialized imaging system, potential drug side effects as well as the limited number of repetitions due to long decay time of ICG in blood circulation. In particular the last drawback prevents brain parenchymal perfusion monitoring with ICG VA. The application of time-resolved thermography as a fast, contactless, noninvasive, marker-free and harmless imaging tool became a promising approach for perfusion imaging and thus offers several advantages compared to ICG. Measurements of deep structures in heat traps for identification of i nternal patterns, e ssential f or e .g. s uccess monitoring of aneurysm clipping, are still unsolved challenges of thermography. This work reveals as a proof of concept that the combination of thermography and an intravenous cold saline bolus injection as a contrast agent is capable to detect arterial and parenchymal perfusion located in the surgical cavity during aneurysm surgery in comparison to state-of-the-art ICG VA. The investigations provide evidence that thermography has the capability to perform intraoperative imaging of cerebral perfusion at an advanced stage in surgery for vessels and parenchyma located both cortically and in the surgical cavity.

Keywords: thermography; aneurysm clipping; neurosurgery; intraoperative thermal imaging; indocyanine green; video angiography

About the article

Published Online: 2018-09-22

Published in Print: 2018-09-01


Citation Information: Current Directions in Biomedical Engineering, Volume 4, Issue 1, Pages 29–32, ISSN (Online) 2364-5504, DOI: https://doi.org/10.1515/cdbme-2018-0008.

Export Citation

© 2018 by Walter de Gruyter Berlin/Boston.Get Permission

Comments (0)

Please log in or register to comment.
Log in