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Current Directions in Biomedical Engineering

Joint Journal of the German Society for Biomedical Engineering in VDE and the Austrian and Swiss Societies for Biomedical Engineering

Editor-in-Chief: Dössel, Olaf

Editorial Board: Augat, Peter / Buzug, Thorsten M. / Haueisen, Jens / Jockenhoevel, Stefan / Knaup-Gregori, Petra / Kraft, Marc / Lenarz, Thomas / Leonhardt, Steffen / Malberg, Hagen / Penzel, Thomas / Plank, Gernot / Radermacher, Klaus M. / Schkommodau, Erik / Stieglitz, Thomas / Urban, Gerald A.


CiteScore 2018: 0.47

Source Normalized Impact per Paper (SNIP) 2018: 0.377

Open Access
Online
ISSN
2364-5504
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Influence of additives on physico-chemical properties of electrospun poly(L-lactide)

Daniela Arbeiter
  • Corresponding author
  • Institute for Biomedical Engineering, Rostock University Medical Center, Rostock, Rostock- Warnemünde, Germany
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/ Stefanie Kohse
  • Institute for Biomedical Engineering, Rostock University Medical Center, Rostock, Rostock- Warnemünde, Germany
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/ Thomas Eickner
  • Institute for Biomedical Engineering, Rostock University Medical Center, Rostock, Rostock- Warnemünde, Germany
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/ Nils Grabow
  • Institute for Biomedical Engineering, Rostock University Medical Center, Rostock, Rostock- Warnemünde, Germany
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/ Klaus-Peter Schmitz
  • Institute for ImplantTechnology and Biomaterials e.V. and Institute for Biomedical Engineering, Rostock University Medical Center, Rostock, Friedrich-Barnewitz- Strasse 4, Rostock- Warnemünde, Germany
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Published Online: 2018-09-22 | DOI: https://doi.org/10.1515/cdbme-2018-0118

Abstract

Electrospun poly(L-lactide) (PLLA) nonwoven represent potential options for biodegradable medical implants. They can be manufactured with high reproducibility and do offer the potential for chemical modification to alter matrix properties. In our study, we investigate the mechanical, thermal and morphological properties of PLLA fiber matrices. Fibrous nonwovens were fabricated from polymer solution by needle electrospinning. The polymer solutions were loaded with Triton X-100 (TX- 100), formic acid and tetraethyl ammonium chloride (TEAC) with respect to polymer weight. Morphology of the PLLA nonwoven scaffolds was examined with SEM. We performed uniaxial tensile tests and differential scanning calorimetry (DSC). Different concentrations of the additives TEAC, formic acid and Triton X-100 lead to strong changes regarding mechanical and thermal properties of the electrospun PLLA fiber matrices. In comparison with mechanical properties of established biological tissue materials, the results indicate the suitability for medical applications.

Keywords: PLLA; electrospinning; fiber diameter; additives; physico chemical properties

About the article

Published Online: 2018-09-22

Published in Print: 2018-09-01


Citation Information: Current Directions in Biomedical Engineering, Volume 4, Issue 1, Pages 493–496, ISSN (Online) 2364-5504, DOI: https://doi.org/10.1515/cdbme-2018-0118.

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