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Open Chemistry

formerly Central European Journal of Chemistry


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Volume 8, Issue 1

Issues

Volume 13 (2015)

Synthesis and characterization of some chalcones and their cyclohexenone derivatives

Thekke Sreevidya
  • Department of Post-Graduate Studies and Research in Chemistry, Mangalore University, Mangalagangotri, 574 199, India
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/ Badiadka Narayana
  • Department of Post-Graduate Studies and Research in Chemistry, Mangalore University, Mangalagangotri, 574 199, India
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/ Hemmige Yathirajan
Published Online: 2010-02-16 | DOI: https://doi.org/10.2478/s11532-009-0124-x

Abstract

A series of chalcones and their derivatives have been synthesized. Chalcones, 1-(1,3-benzodioxol-5-yl)-3-(aryl)-prop-2-en-1-ones were prepared by the aldol condensation of 1-(1,3-benzodioxol-5-yl)ethanones and aryl aldehydes. Based-catalyzed condensation of 1-(1,3-benzodioxol-5-yl)-3-(aryl)prop-2-en-1-ones with ethyl acetoacetate yields corresponding ethyl 4-(1,3-benzodioxol-5-yl)-6-(aryl)-2-oxocyclohex-3-ene-1-carboxylates. Some of the synthesized chalcones were reported in the literature; the newly synthesized compounds were characterized by single crystal X-ray studies, IR, 1H-NMR and LCMS mass spectral analysis.

Keywords: Chalcones; Michael addition; Single crystal XRD; Cyclohexenones

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About the article

Published Online: 2010-02-16

Published in Print: 2010-02-01


Citation Information: Open Chemistry, Volume 8, Issue 1, Pages 174–181, ISSN (Online) 2391-5420, DOI: https://doi.org/10.2478/s11532-009-0124-x.

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© 2010 Versita Warsaw. This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License. BY-NC-ND 3.0

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