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Open Chemistry

formerly Central European Journal of Chemistry

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Volume 13, Issue 1


Volume 13 (2015)

Determination of micelle aggregation numbers of alkyltrimethylammonium bromide and sodium dodecyl sulfate surfactants using time-resolved fluorescence quenching

Martin Pisárčik
  • Corresponding author
  • Department of Chemical Theory of Drugs, Faculty of Pharmacy, Comenius University, Kalinčiakova 8, SK-83232 Bratislava, Slovakia
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Ferdinand Devínsky
  • Department of Chemical Theory of Drugs, Faculty of Pharmacy, Comenius University, Kalinčiakova 8, SK-83232 Bratislava, Slovakia
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Matúš Pupák
  • Department of Chemical Theory of Drugs, Faculty of Pharmacy, Comenius University, Kalinčiakova 8, SK-83232 Bratislava, Slovakia
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
Published Online: 2015-05-27 | DOI: https://doi.org/10.1515/chem-2015-0103


The time-resolved fluorescence quenching method was applied to determine the micelle aggregation number of cationic single-chain surfactants dodecyltrimethylammonium bromide (DTAB), cetyltrimethylammonium bromide (CTAB) and anionic surfactant sodium dodecyl sulfate (SDS). The concentration dependence of micelle aggregation number was found to be linear for all investigated surfactants in the concentration range 2‒15 × the value of critical micelle concentration of the respective surfactant. The values of micelle aggregation number were found in the range 30‒77. Different trends in the linear concentration dependence of micelle aggregation number were observed for cationic surfactants and for the anionic surfactant SDS. A small slope value was found for cationic surfactants, while the SDS micelle aggregation number concentration dependence showed significantly a larger slope value. The aggregation number increase with the increasing SDS concentration results in the micellar growth. Results from a simple analysis based on computer models of cationic and anionic surfactant molecules with dodecyl chains supports, the formation of intramicellar hydrogen bonding between surfactant molecules in SDS micelle shell.

Graphical Abstract

Keywords : micelle aggregation number; fluorescence quenching; sodium dodecyl sulfate; hydrogen bonding


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About the article

Received: 2014-09-27

Accepted: 2015-03-19

Published Online: 2015-05-27

Citation Information: Open Chemistry, Volume 13, Issue 1, ISSN (Online) 2391-5420, DOI: https://doi.org/10.1515/chem-2015-0103.

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© 2015 Martin Pisárčik et al.. This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License. BY-NC-ND 3.0

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