Jump to ContentJump to Main Navigation
Show Summary Details
More options …

Open Chemistry

formerly Central European Journal of Chemistry

1 Issue per year


IMPACT FACTOR 2016 (Open Chemistry): 1.027
IMPACT FACTOR 2016 (Central European Journal of Chemistry): 1.460

CiteScore 2016: 0.61

SCImago Journal Rank (SJR) 2016: 0.288
Source Normalized Impact per Paper (SNIP) 2016: 0.735

Open Access
Online
ISSN
2391-5420
See all formats and pricing
More options …
Volume 13, Issue 1 (Nov 2015)

Issues

Qualitative and quantitative analysis of polyphenolic compounds in Ilex Sp.

Anna Zwyrzykowska
  • Corresponding author
  • Department of Environment Hygiene and Animal Welfare, The Faculty of Biology and Animal Science
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Robert Kupczyński
  • Department of Environment Hygiene and Animal Welfare, The Faculty of Biology and Animal Science
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Bogdan Jarosz / Antoni Szumny / Alicja Z. Kucharska
  • Departament of Fruit, Vegetable and Cereals Technology, The Faculty of Food Science and Technology, Wrocław University of Environmental and Life Sciences
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
Published Online: 2015-11-30 | DOI: https://doi.org/10.1515/chem-2015-0142

Abstract

Natural compounds are an important source of desired biological activity which help to improve nutritional status, enhance productivity and bring many health benefits. The leaves of the Ilex paraguariensis (Aquifoliaceae) are used for preparing a beverage known as yerba mate and represent a proven source of natural polyphenols which are known to foster biological activity with the emphasis on antioxidant properties. In present work we focused on the polyphenolic content of air-dried leaves of Ilex aquifolium L., Ilex aquifolium ‘Argentea Mariginata’, Ilex meserveae ‘Blue Angel’, and a commercially available mate as the reference product. Liquid chromatography combined with mass spectrometry (HPLC and LC-MS) and thin layer chromatography (TLC), were used to establish polyphenolic substances content in aqueous methanolic extracts obtained from the biological matter. Up to 20 polyphenolic compounds were identified in the extracts, including rutin, quinic acid and its caffeoyl esters, i.e. chlorogenic acid and its isomers as well as dicaffeoyl derivatives. We took chlorogenic acid and rutin as reference compounds to quantify their levels in the extracts. It was determined that in all tested plants, high levels of these antioxidants were present. This led us to the conclusion that their leaves might serve as valuable food additives.

Keywords : Ilex sp.; extraction; polyphenols; HPLC MS

References

  • [1] Cogo L., Giacomino M.S., Pellegrino N., Anesini C., Filip R., Nutritional and Phytochemical Study of Ilex paraguariensis Fruits, J. Chem., 2013, 750623, 6. Web of ScienceGoogle Scholar

  • [2] Pasquali T.R., Macedo S.M.D., Roman S.S., Dal Prá V., Cansian R.L., et al., Acute toxicity and anti inflammatory effects of supercritical extracts of Ilex paraguariensis, Afr. J. Pharm. Pharmacol., 2011, 5, 1162-1169. Google Scholar

  • [3] Cansian R.L., Mossi A.J., Mazutti M.A., Oliveira J.V., Paroul N., Dariva C., et al., Semi-volatile compounds variation among Brazilian populations of Ilex paraguariensis St Hill.), Braz. Arch. Biol. Technol., 2008, 51, 175-181. Google Scholar

  • [4] Cansian R.L., Mossi A.J., Mosele S.H., Toniazzo G., Treichel H., Paroul N., et al., Genetic conservation and medicinal properties of mate (Ilex paraguariensis St Hil.), Pharmacogn. Rev.,2008, 2, 326-338. Google Scholar

  • [5] Bracesco N., Sanchez A.G., Contreras V., Menini T., Gugliucci A., Recent advances on Ilex paraguariensis research: Minireview, J. Ethnopharmacol., 2011, 136, 378-384. Web of ScienceGoogle Scholar

  • [6] da Silva Lima L., de Oliveira E., Santos da Silva A.P., de Albuquerque Maia L., de Moura E.G., et al., Effects of Ilex paraguariensis (yerba mate) treatment on leptin resistance and inflammatory parameters in obese rats primed by early weaning, Life Sci., 2014, 115, 29-35. Google Scholar

  • [7] Balzan S., Hernandes A., Loiva Reichert C., Donaduzzi C., Aranega Pires V., Gasparotto Junior A., et al., Lipid-lowering effects of standardized extracts of Ilex paraguariensis in high-fat-diet rats, Fitoterapia, 2013, 86, 115-122. Web of ScienceGoogle Scholar

  • [8] Deladino L., Schneider Teixeira A., Reta M., Molina García A.D., Navarro A.S., Martino M.N., Major Phenolics in Yerba Mate Extracts (Ilex paraguariensis) and Their Contribution to the Total Antioxidant Capacity, Food and Nutrition Sciences, 2013, 4, 154-162. Google Scholar

  • [9] Puangpraphant S., Berhow M.A., de Mejia E., Yerba mate (Ilex paraguariensis St. Hilaire) saponins inhibit human colon cancer cell proliferation, ACS Symposium Series. 2012, 1109, 307-321. Google Scholar

  • [10] Celi P., Raadsma H.W., Effects of Yerba Mate (Ilex paraguariensis) supplementation on the productive performance of dairy cows Turing mid-lactation, Anim. Prod. Sci., 2010, 50, 339-344. Google Scholar

  • [11] Celi P., Robinson A., Effects of Yerba Mate (Ilex paraguariensis) supplementation on the performance of dairy calves, Anim. Prod. Sci., 2010, 50, 376-381. Web of ScienceGoogle Scholar

  • [12] Bravo L., Goya L., Lecumberri E., LC/MS characterization of phenolic constituents of mate (Ilex paraguariensis, St. Hil.) and its antioxidant activity compared to commonly consumed beverages, Food Res. Int., 2007, 40, 393-405. Web of ScienceGoogle Scholar

  • [13] Grujic N., Lepojevic Z., Srdjenovic B., Vladic J., Sudji J., Effects of different extraction methods and conditions on the phenolic composition of mate tea extracts, Molecules, 2012,17, 2518-2528. Web of ScienceGoogle Scholar

  • [14] Heck C.I., de Mejia E.G., Yerba Mate Tea (Ilex paraguariensis), a comprehensive review on chemistry, health implications, and technological considerations, J. Food Sci., 2007, 72, R138-R151. Web of ScienceGoogle Scholar

  • [15] Erol N.T., Sari F., Calikoğlu E., Velİoğlu Y., Green and roasted mate: phenolic profile and antioxidant activity, Turk J. Agric, 2009, 33, 353-362. Web of ScienceGoogle Scholar

  • [16] Fang N., Yu S., Prior R.L., LC/MS/MS characterization of phenolic constituents in dried plums, J. Agric. Food Chem., 2002, 50, 3579-3585 Google Scholar

  • [17] Filip R., Lotito S.B., Ferraro G., Fraga C.G., Antioxidant activity of Ilex paraguariensis and related species, Nutr. Res., 2000, 20,1437-1446. Google Scholar

  • [18] Yoshimoto M., Yahara S., Okuno S., Islam M.S., Ishiguro K., et al., Antimutagenicity of mono-, di- and tricaffeoylquinic acid derivates isolated from sweet potato (Ipomoca batatas L.) leaf, Biosci. Biotechnol. Biochem., 2002, 66, 2336-2341. Google Scholar

  • [19] Islam M. S., Yoshimoto M., Yamakawa O., Distribution and physiological functions of caffeoylquinic acid derivatives in leaves of sweet potato genotypes, 2003, J. F. S., 68,111-116. Google Scholar

  • [20] Plazonić A., Bucar F., Maleš Ž., Mornar A., Nigowić B., Kujundžić N., Identification and Quantification of Flavonoids and Phenolic Acids in Burr Parsley (Caucalis platycarpos L.), Using High-Performance Liquid Chromatography with Diode Array Detection and Electrospray Ionization Mass Spectrometry, Molecules, 2009, 14, 2466-2490 CrossrefWeb of ScienceGoogle Scholar

  • [21] Ueno I., Kohno M., Haraikawa K., Hiromo I., Interactions between quercetin and superoxide radicals. Reduction of quercetin mutagenicity, J. Pharmacobio-dyn., 1984, 7, 788–803. Google Scholar

  • [22] Morel L., Lescoat G., Cogrel P., Sergeant O., Pasdeloup N., Brisot P., et al., Anti-oxidant and iron-chelating activities of the flavonoids catechins, quercetin and diosmetin on iron-loaded rat hepatocyte cultures, Biochem. Pharmacol., 1993, 45,13-19. Google Scholar

  • [23] Ramirez-Mares M., Chandra S., Gonzalez de Mejia E., In vitro chemopreventive activity of Camellia sinensis, Ilex paraguariensis and Ardisia compressa tea extracts and selected polyphenols, Mutation Research, 2004, 554, 53-65. Google Scholar

  • [24] Jaiswal R., Sovdat T., Vivan F., Kuhnert N., Profiling and Characterization by LC-MSn of the Chlorogenic Acids and Hydroxycinnamoylshikimate Esters in Mate (Ilex paraguariensis), J. Agric. Food Chem., 2010, 58, 5471-5484 Web of ScienceGoogle Scholar

  • [25] Onakpoya I.J., Spencer E.A., Thompson M.J., Heneghan C.J., The effect of chlorogenic acid on blood pressure: a systematic review and meta-analysis of randomized clinical trials,. J. Hum. Hypertens., 2015, 29, 77-81. Web of ScienceGoogle Scholar

  • [26] Kessler M., Ubeaud G., Jung L., Anti- and pro-oxidant activity of rutin and quercetin derivatives, J. Pharm. Pharmacol., 2003, 55, 131-142. Google Scholar

About the article

Received: 2015-02-15

Accepted: 2015-10-01

Published Online: 2015-11-30


Citation Information: Open Chemistry, ISSN (Online) 2391-5420, DOI: https://doi.org/10.1515/chem-2015-0142.

Export Citation

© 2015 Anna Zwyrzykowska et al.. This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License. BY-NC-ND 3.0

Comments (0)

Please log in or register to comment.
Log in