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Volume 65, Issue 5


One-pot synthesis of 2-amino-3-cyano-4-arylsubstituted tetrahydrobenzo[b]pyrans catalysed by silica gel-supported polyphosphoric acid (PPA-SiO2) as an efficient and reusable catalyst

Abolghasem Davoodnia / Sadegh Allameh / Samineh Fazli / Niloofar Tavakoli-Hoseini
Published Online: 2011-07-23 | DOI: https://doi.org/10.2478/s11696-011-0064-8


A convenient method for the synthesis of tetrahydrobenzo[b]pyrans by a one-pot three-component cyclocondensation of dimedone, aryl aldehydes, and malononitrile in water using silica gel-supported polyphosphoric acid (PPA-SiO2) as an efficient and reusable catalyst is described. The present methodology offers several advantages, such as a simple procedure with ease of handling, short reaction time, high yields, and the absence of any volatile and hazardous organic solvents.

Keywords: tetrahydrobenzo[b]pyrans; PPA-SiO2; heterogeneous catalysis; aqueous media

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About the article

Published Online: 2011-07-23

Published in Print: 2011-10-01

Citation Information: Chemical Papers, Volume 65, Issue 5, Pages 714–720, ISSN (Online) 1336-9075, DOI: https://doi.org/10.2478/s11696-011-0064-8.

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