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Volume 66, Issue 8

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Reduction of aromatic nitro compounds to amines using zinc and aqueous chelating ethers: Mild and efficient method for zinc activation

Pookot Kumar
  • FMC (I) R&D Centre, Society for Innovation and Development, Indian Institute of Science Campus, 560012, Bangalore, India
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/ Kuriya Lokanatha Rai
Published Online: 2012-06-19 | DOI: https://doi.org/10.2478/s11696-012-0195-6

Abstract

A mild, environmentally friendly method for reduction of aromatic nitro group to amine is reported, using zinc powder in aqueous solutions of chelating ethers. The donor ether acts as a ligand and also serves as a co-solvent. Water is the proton source. This procedure is also a new method for the activation of zinc for electron transfer reduction of aromatic nitro compounds. The reduction is accomplished in a neutral medium and other reducing groups remained unaffected. The ethers used are dioxolane, 1,4-dioxane, ethoxymethoxyethane, dimethoxymethane, 1,2-dimethoxyethane, and diglyme.

Keywords: reduction; dioxolane; chelating ether; aqueous medium; zinc

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About the article

Published Online: 2012-06-19

Published in Print: 2012-08-01


Citation Information: Chemical Papers, Volume 66, Issue 8, Pages 772–778, ISSN (Online) 1336-9075, DOI: https://doi.org/10.2478/s11696-012-0195-6.

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© 2012 Institute of Chemistry, Slovak Academy of Sciences.

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