IMPACT FACTOR 2015: 1.326
SCImago Journal Rank (SJR) 2015: 0.382
Source Normalized Impact per Paper (SNIP) 2015: 0.560
Impact per Publication (IPP) 2015: 1.279
Synthesis of new aryl(hetaryl)-substituted tandospirone analogues with potential anxiolytic activity via reductive Heck type hydroarylations
1338Department of Chemistry, Yildiz Technical University, Faculty of Science and Arts, Davutpasa Campus, 34220, Esenler, Istanbul, Turkey
2338Institute of Organic Chemistry, University of Technology, Leibnizstr. 6, Clausthal, D-38678, Clausthal-Zellerfeld, Germany
Citation Information: Chemical Papers. Volume 67, Issue 6, Pages 643–649, ISSN (Online) 1336-9075, DOI: 10.2478/s11696-013-0338-4, March 2013
- Published Online:
Tandospirone (I), developed as an anxiolytic drug, is an aryl-piperazine compound that binds to both 5-HT1A and dopamine D4 receptors. Palladium-catalysed hydroarylation reactions of tandospirone analogues containing an oxygen bridge and 3-(trifluoromethyl)phenyl or 2,3-dichlorophenyl groups were studied in order to find a new stereoselective access to a series of new exo-aryl(hetaryl)-substituted derivatives with potential biological activity.
Here you can find all Crossref-listed publications in which this article is cited. If you would like to receive automatic email messages as soon as this article is cited in other publications, simply activate the “Citation Alert” on the top of this page.