Jump to ContentJump to Main Navigation
Show Summary Details
More options …

Acta Chirurgica Latviensis

The Journal of Riga Stradins University; Latvian Association of Surgeons; Latvian Association of Paediatric Surgeons

2 Issues per year

Open Access
Online
ISSN
2199-5737
See all formats and pricing
More options …

Primary Bronchus-Associated Lymphoid Tissue (BALT) Lymphoma

Andrejs Vanags / Jelena Grusina-Ujumaza / Ilze Strumfa / Genadijs Ambalovs / Arnis Abolins / Janis Gardovskis
Published Online: 2012-07-13 | DOI: https://doi.org/10.2478/v10163-012-0028-2

Primary Bronchus-Associated Lymphoid Tissue (BALT) Lymphoma

Bronchus-associated lymphoid tissue (BALT) lymphoma is a rare extra-nodal marginal zone lymphoma representing 0.5% of lung tumours. In order to share experience in the management of BALT lymphoma, we report a well-investigated case with unusual features as complex familial oncologic history and synchronous benign thyroid disease. The patient was a 44-year-old woman with prolonged unspecific respiratory complaints. By computed tomography (CT), bilateral atelectasis-like pulmonary lesions were found in the 3rd, 5th, 6th and 8th segments of the right lung and in the 3rd segment of the left lung. We performed diagnostic video-assisted wedge resection of the 5th segment of right lung. Pathologic and immunohistochemical examination yielded the diagnosis of BALT lymphoma. After staging by bone marrow biopsy and abdominal CT, chemotherapy was recommended by the oncologic council.

Keywords: bronchus-associated lymphoid tissue; BALT lymphoma; lung tumour

  • Ahmed S, Kussick SJ, Siddiqui AK, Bhuiya TA, Khan A, Sarewitz S, Steinberg H, Sison CP, Rai KR. Bronchial-associated lymphoid tissue lymphoma: a clinical study of a rare disease // Eur J Cancer, 2004; 40(9):1320-1326PubMedCrossrefGoogle Scholar

  • Arnaoutakis K, OoTh. Bronchus-associated lymphoid tissue lymphomas // South Med J, 2009; 102(12):1229-1233CrossrefPubMedWeb of ScienceGoogle Scholar

  • Bernabeu MR, Sánchez JM, Nieto OA. Bilateral pulmonary nodules as a manifestation of primary pulmonary T-cell lymphoma // Int J Hematol, 2009; 90(2):153-156Web of ScienceCrossrefGoogle Scholar

  • Bilici A, Seker M, Ustaalioglu BB, Canpolat N, Salepci T, Gumus M. Pulmonary BALT lymphoma successfullty treated with eight cycles weekly rituximab: report of first case and F-18 FDG PET/CT images // J Korean Med Sci, 2011; 26(4):574-576Web of ScienceCrossrefGoogle Scholar

  • Gaur S, Trayner, Aish L, Weinstein R. Bronchus-associated lymphoid tissue lymphoma arising in a patient with bronchiectasis and chronic Mycobacterium avium infection // Am J Hematol, 2004; 77(1):22-25CrossrefGoogle Scholar

  • Imai H, Sunaga N, Kaira K, Kawashima O, Yanagitani N, Sato K, Tomizawa Y, Hisada T, Ishizuka T, Hirato J, Saito R, Nakajima T, Mori M. Clinicopathological features of patients with bronchial-associated lymphoid tissue lymphoma // Intern Med, 2009; 48(5):301-306PubMedWeb of ScienceCrossrefGoogle Scholar

  • Milosevic V, Bogdanovic A, Jankovic S, Jovanovic MP, Mihaljevic B. Extranodal marginal zone non Hodgkin's lymphoma of the lung: a ten-year experience // Vojnosanit Pregl, 2011; 68(2):150-154Web of ScienceCrossrefGoogle Scholar

  • Okamoto M, Inaba T, Uchida R, Fuchida S, Ochiai N, Okano A, Ashihara E, Inagaki H, Nakamura S, Shimazaki C. Human immunodeficiency virus (HIV)-negative, API2-MALT1 fusion-negative bronchus-associated lymphoid tissue (BALT) lymphoma in a young male // Leuk Lymphoma, 2004; 45(10):2165-2168Google Scholar

  • Sakuraba M, Onuki T, Mae M, Yoshida T, Nitta S. Three cases of primary pulmonary malignant lymphoma // Nihon Kokyuki Gakkai Zasshi 2000; 38(9):714 - 719. Pubmed abstract PMID11109812Google Scholar

  • Stefanovic A, Morgensztern D, Fong T, Lossos IS. Pulmonary marginal zone lymphoma: a single centre experience and review of the SEER database // Leuk Lymphoma, 2008; 49(7):1311-1320CrossrefWeb of SciencePubMedGoogle Scholar

  • Takamori M, Noma S, Kobashi Y, Inoue T, Gohma I, Mino M, Taguchi Y. CT findings of BALTOMA // Radiat Med, 1999; 17(5):349-54PubMedGoogle Scholar

About the article


Published Online: 2012-07-13

Published in Print: 2011-01-01


Citation Information: Acta Chirurgica Latviensis, Volume 11, Issue 1, Pages 144–147, ISSN (Print) 1407-981X, DOI: https://doi.org/10.2478/v10163-012-0028-2.

Export Citation

This content is open access.

Comments (0)

Please log in or register to comment.
Log in