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Current Issues in Pharmacy and Medical Sciences

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Essential oil composition and variability of Hypericum perforatum L. from wild population in Kosovo

Avni Hajdari
  • Department of Biology, Faculty of Mathematical and Natural Science, University of Prishtina “Hasan Prishtina”, Mother Theresa 10000 Prishtine, Kosovo
  • Other articles by this author:
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/ Behxhet Mustafa
  • Department of Biology, Faculty of Mathematical and Natural Science, University of Prishtina “Hasan Prishtina”, Mother Theresa 10000 Prishtine, Kosovo
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/ Dashnor Nebija
  • Department of Pharmacy, Faculty of Medicine, University of Prishtina “Hasan Prishtina”, Bulevardi i Deshmoreve, 10 000 Prishtine, Kosovo
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/ Albana Kashtanjeva
  • Department of Biology, Faculty of Mathematical and Natural Science, University of Prishtina “Hasan Prishtina”, Mother Theresa 10000 Prishtine, Kosovo
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/ Jaroslaw Widelski
  • Department of Pharmacogosy with Medicinal Plants Laboartory, Medical Univeristy of Lublin Chodzki 1, 20-093 Lublin, Poland
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/ Kazimierz Glowniak
  • Department of Pharmacogosy with Medicinal Plants Laboartory, Medical Univeristy of Lublin Chodzki 1, 20-093 Lublin, Poland
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/ Johannes Novak
  • Institute of Animal Nutrition and Functional Plant Compounds, University of Veterinary Medicine, Veterinarplatz 1, 1210 Vienna, Austria
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Published Online: 2014-05-30 | DOI: https://doi.org/10.2478/cipms-2014-0013

Abstract

Aerial parts of Hypericum perforatum L. (Hypericaceae) were collected from five wild populations in Kosovo, with aim to investigate the chemical composition and natural variation of essential oils between wild populations. This species could be considered of economic potential as it is widespread in Kosovo, on the other hand H. perforatum is one of the best-known medicinal herbs used in Kosovo folk medicine. Essential oils were obtained by steam distillation and analysed by GC-FID and GC-MS. Sixty-seven components were identified. The yields of essential oils differed depending on the population and ranged from 0.04 to 0.26% based on dry weight. The aerial parts of H. perforatum were characterized by the following main constituents: 2-methyl-octane (1.1-15.5%), α-pinene (3.7-36.5%), β-caryophyllene (1.2-12.4%), caryophyllene oxide (3.3-17.7%) and n-tetradecanol (3.6- 10.4%). Hierarchical cluster analysis revealed that the concentration of components depends on the origin of the plant populations, thus α-pinene and 2-methyl-octane were present in the highest concentration in population originating from Gjakove, Prizren and Ferizaj, whereas in the populations originating from Peje and Prishtine the most abundant constituents were caryophyllene oxide, β-caryophyllene and n-tetradecanol. Further investigation is needed to establish the natural variability and chemopolymorphism of this species in the territory of Kosovo, which should be supported by molecular level analyses.

Keywords: essential oil; Hypericum perforatum; Kosovo; natural variability

References

  • 1. Adams RP. (2009). Identification of Essential Oil Components by Gas Chromatography/Mass Spectrometry. 4th Edn., Allured Publishers, Carol Stream, IL., USA.Google Scholar

  • 2. Baser K.H.C., Ozek T., Nuriddinov H.R., Demirci A.B.: Essential oil of two Hypericum species from Uzbekistan. Chem. Nat. Compd., 38:1, 54-57, 2002.CrossrefGoogle Scholar

  • 3. Bradley, P. British Herbal Compendium. Vol 2. British Herbal Medicin Association, 2006.Google Scholar

  • 4. Cakir A., Duru M.E., Harmandar M., Ciriminna R., Passannanti S., Piozzi F., Comparison of the volatile oils of Hypericum scabrum L. and Hypericum perforatumin Turkey. Flavour Fragrance J., 12, 285-287, 1997.Google Scholar

  • 5. Crockett S.L., Robson N.K.: Taxonomy and chemotaxonomy of the genus Hypericum Med. Aromat. Plant Sci. Biotechnol., 5, 1-13, 2011.Google Scholar

  • 6. Erken S., Malyer H., Demirci F., Demirci B., Baser K.H.C., Chemical investigations on some Hypericumspecies growing in Turkey-I.Chem. Nat. Compd., 37, 434-438, 2002.Google Scholar

  • 7. European Pharmacopeia. (2011). European Pharmacopoeia. 6th Edn., Maisonneuve Publishers, Strasbourg, France.Google Scholar

  • 8. Hobbs C.: St. John’s wort, Hypericum perforatum L. Herbalgram, 18, 24-33, 1989.Google Scholar

  • 9. Mahady G.B., Fong H.H.S., Farnsworth N.R. (2001). WHO monographs of selected medicinal plants II. World Health Organization, Geneva, Switzerland.Google Scholar

  • 10. Mimica-Dukic N., Ivancev-Tumbas I., Igic R., Popovic M., Gasic O.: The content and composition of essential oil of Hypericum perforatumfrom Serbia. Pharm. Pharmacol. Lett., 8, 26-28, 1997.Google Scholar

  • 11. Mustafa B., Hajdari A., Krasniqi F., Hoxha E., Ademi H., Quave C.L., Pieroni A., Medical ethnobotany of the Albanian Alps in Kosovo.J. Ethnobiol. Ethnomed., 8:6, 1-14, 2012.Web of ScienceGoogle Scholar

  • 12. Mustafa B., Hajdari A., Pajazita Q., Syla B., Quave C.L., Pieroni A., An ethnobotanical survey of the Gollak region, Kosovo. Gen. Resour.Crop Evol., 59, 739-754, 2012.Google Scholar

  • 13. Nahrstedt A, Butterweck V. Biologically active and other chemical constituents of the herb of Hypericum perforatum L.Pharmacopsychiatry, 30, 129-134, 1997.Google Scholar

  • 14. Schwob I., Bessiere J.M., Viano, J. Composition of the essential oils of Hypericum perforatum L. from Southeastern France. C.R.Biologies, 325, 781-785, 2002.Google Scholar

  • 15. Smelcerovic A., Spiteller M., Ligon A.P., Smelcerovic Z., Raabe N.: Essential oil composition of Hypericum L. species from Southeastern Serbia and their chemotaxonomy. Biochem. Syst. Ecol., 35, 99-113, 2007.Web of ScienceGoogle Scholar

  • 16. Tutin G.T., Haywood H.V., Burges A.N., Moore D.M., Valentine D.H., Walters S.M., Webb D.A. (1972) Flora Europea. Vol. 3, Cambridge University Press, Cambridge, UK.Google Scholar

  • 17. Vasileva R., Georgieva V., Vojnova J., Milkova T.: GC-MS study on the essential oils of Bulgarian Hypericum maculatum Grantz and Hypericum perforatum L. Comptes Rendus Academie Bulgare Sciences, 56, 71-74, 2003.Google Scholar

  • 18. Wichtl, M. Teedrogen. Wissenschaftliche Verlagsgesellschaft mbH, Stuttgart, 4. Auflage 2002.Google Scholar

About the article

Received: 2014-02-14

Accepted: 2014-03-24

Published Online: 2014-05-30

Published in Print: 2014-06-01


Citation Information: Current Issues in Pharmacy and Medical Sciences, Volume 27, Issue 1, Pages 51–54, ISSN (Online) 2300-6676, ISSN (Print) 2084-980X, DOI: https://doi.org/10.2478/cipms-2014-0013.

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© 2014. This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License. BY-NC-ND 3.0

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