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Drug Metabolism and Personalized Therapy

Official journal of the European Society of Pharmacogenomics and Personalised Therapy

Editor-in-Chief: Llerena, Adrián

Editorial Board: Benjeddou, Mongi / Chen, Bing / Dahl, Marja-Liisa / Devinsky, Ferdinand / Hirata, Rosario / Hubacek, Jaroslav A. / Ingelman-Sundberg, Magnus / Maitland-van der Zee, Anke-Hilse / Manolopoulos, Vangelis G. / Marc, Janja / Melichar, Bohuslav / Meyer, Urs A. / Nair, Sujit / Nofziger, Charity / Peiro, Ana / Sadee, Wolfgang / Salazar, Luis A. / Simmaco, Maurizio / Turpeinen, Miia / Schaik, Ron / Shin, Jae-Gook / Visvikis-Siest, Sophie / Zanger, Ulrich M.

CiteScore 2018: 1.01

SCImago Journal Rank (SJR) 2018: 0.277
Source Normalized Impact per Paper (SNIP) 2018: 0.446

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Volume 31, Issue 2


Volume 34 (2019)

The integration and interpretation of pharmacogenomics – a comparative study between the United States of America and Europe: towards better health care

Mark J. Bartlett / Elizabeth A. Shephard
  • Institute of Structural and Molecular Biology, University College London, Gower Street, London, UK
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
Published Online: 2016-06-07 | DOI: https://doi.org/10.1515/dmpt-2015-0044


The study of pharmacogenomics has, by harnessing sequence information from human genomes, the potential to lead to novel approaches in drug discovery, an individualized application of drug therapy, and new insights into disease prevention. For this potential to be realized results need to be interpreted to the prescriber into a format which dictates an action. This mini review briefly describes the history, the regulatory environment, opinions towards, and implementation, integration and interpretation of pharmacogenomics in the United States of America and Europe. The article discusses also how interpretation of pharmacogenomics could move forward to better implementation in health care.

Keywords: implementation; pharmacogenetics; pharmacogenomics; regulatory bodies


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About the article

Received: 2015-12-04

Accepted: 2016-04-06

Published Online: 2016-06-07

Published in Print: 2016-06-01

Citation Information: Drug Metabolism and Personalized Therapy, Volume 31, Issue 2, Pages 91–96, ISSN (Online) 2363-8915, ISSN (Print) 2363-8907, DOI: https://doi.org/10.1515/dmpt-2015-0044.

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