Hermann R, Richter O. Clinical evidence of herbal drugs as perpetrators of pharmacokinetic drug interactions. Planta Medica 2012;78:1458–77.Google Scholar
Yamsani SK, Devandla A, Dharani S, Gannu R, Athukuri BL, Palem CR, et al. P-Glycoprotein- and cytochrome P-450-mediated herbal drug Interactions. Drug Metab Drug Interact 2010;25:3–16.Google Scholar
Claudine M, Augustin S, Christine M, Christian R, Liliana J. Polyphenols: food sources and bioavailability. Am J Clin Nutr 2004;79:727–47.Google Scholar
An-Na L, Sha L, Yu-Jie Z, Xiang-Rong X, Yu-Ming C, Hua-Bin Li. Resources and biological activities of natural polyphenols. Nutrients 2014;6:6020–47.Google Scholar
Mansouri MT, Soltani M, Naghizadeh B, Farbood Y, Mashak A, Sarkaki A. A possible mechanism for the anxiolytic-like effect of gallic acid in the rat elevated plus maze. Pharmacol Biochem Behav 2013;117:40–6.Google Scholar
Kim YS, Zerin T, Song HY. Antioxidant action of ellagic acid ameliorates paraquat-induced A549 cytotoxicity. Biol Pharm Bull 2013;36:609–15.Google Scholar
Thangavel MV, Ramasamy MK, Aruna A, Govind PD, Kaliappan I. Comparative inhibitory potential of selected dietary bioactive polyphenols, phytosterols on CYP3A4 and CYP2D6 with fluorometric high-throughput screening. J Food Sci Technol 2015;52:4537–43.Google Scholar
Wacher VJ, Benet ZL. Use of gallic acid esters to increase bioavailability of orally administered pharmaceutical compounds. U.S. Patent US 6180666 B1; 2001.
Giftson SJ, Jayanthi S, Viswanathan P, Umadevi P, Nalini N. Effect of gallic acid on xenobiotic metabolizing enzymes in 1,2-dimethyl hydrazine induced colon carcinogenesis in Wistar rats–a chemopreventive approach. Food Chem Toxicol 2011;49:887–92.Google Scholar
Wang B, Yang LP, Zhang XZ, Huang SQ, Bartlam M, Zhou SF. New insights into the structural characteristics and functional relevance of the human cytochrome P450 2D6 enzyme. Drug Metab Rev 2009;41:573–643.Google Scholar
Sutton SC, Rinaldi MT, Vukovinsky KE. Comparison of the gravimetric, phenol red and 14C-PEG-3350 methods to determine water absorption in the rat single-pass intestinal perfusion model. AAPS Pharm Sci 2001;3:93–7.Google Scholar
Varma MV, Panchagnula R. Prediction of in vivo intestinal absorption enhancement on P-glycoprotein inhibition, from rat in situ permeability. J Pharm Sci 2005;94:1694–704.Google Scholar
Prasad N, Satish KB. Effect of diosmin on the intestinal absorption and pharmacokinetics of fexofenadine in rats. Pharmacol Rep 2015;67:339–44.Google Scholar
Mahvash I, Shoba RH. Estimation of metoprolol in human plasma by HPLC method. Int J Pharm Pharm Sci 2015;7:442–46.Google Scholar
Salphati L, Childers K, Pan L, Tsutsui K, Takahashi L. Evaluation of a single-pass intestinal-perfusion method in rat for the prediction of absorption in man. J Pharm Pharmacol 2001;53:1007–13.Google Scholar
Ekaterina AK. Effect of natural polyphenols on CYP metabolism: implications for diseases. Chem Res Toxicol 2015;28:1359–90.Google Scholar
Ingelman-Sundberg M. Genetic polymorphisms of cytochrome P450 2D6 (CYP2D6): clinical consequences, evolutionary aspects and functional diversity. Pharmacogenomics J 2005;5:6–13.Google Scholar
Bramer SL, Suri A. Inhibition of CYP2D6 by quinidine and its effects on the metabolism of cilostazol. Clin Pharmacokinet 1999;37:41–51.Google Scholar
Ponnusankar S, Subrata P, Ramesh B, Arun B, Pulok KM. Cytochrome P450 inhibitory potential of Triphala–A Rasayana from Ayurveda. J Ethnopharmacol 2011;133:120–5.Google Scholar
About the article
Published Online: 2016-11-22
Published in Print: 2016-12-01
Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.
Research funding: None declared.
Employment or leadership: None declared.
Honorarium: None declared.
Competing interests: The funding organization(s) played no role in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the report for publication.