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Meyer, Alexander von


Official Journal of the Society to Improve Diagnosis in Medicine (SIDM)

Editor-in-Chief: Graber, Mark L. / Plebani, Mario

Ed. by Epner, Paul L. / Lippi, Giuseppe / Singh, Hardeep

Editorial Board: Basso , Daniela / Crock, Carmel / Croskerry, Pat / Dhaliwal, Gurpreet / Ely, John / Giannitsis, Evangelos / Katus, Hugo A. / Laposata, Michael / Lyratzopoulos, Yoryos / Maude, Jason / Newman-Toker, David / Sittig, Dean F. / Singhal, Geeta / Zwaan, Laura

CiteScore 2018: 0.69

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Atrial fibrillation: is there a role for cardiac troponin?

Alireza Sepehri ShamlooORCID iD: https://orcid.org/0000-0002-4894-8664 / Arash Arya / Angeliki Darma / Sotirios Nedios / Michael Döring / Andreas Bollmann / Nikolaos Dagres / Gerhard Hindricks
Published Online: 2020-01-09 | DOI: https://doi.org/10.1515/dx-2019-0072


Atrial fibrillation (AF) is the most common sustained arrhythmia, and its prevalence rate is expected to be doubled over the next decades. Despite the wide use of biomarkers in the management of different cardiac diseases such as myocardial infarction and heart failure, utilization of biomarkers in AF management is not routinely recommended by current guidelines. There is also growing evidence that higher levels of cardiac-specific troponin, as an intracellular protein involved in cardiomyocyte contraction, may be associated with the risk of incident and recurrent AF and its complications. In the present paper, we review the association between troponin and AF and propose clinical suggestions for use of troponin in the management of AF patients.

Keywords: atrial fibrillation; biomarker; risk score; troponin


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About the article

Corresponding author: Alireza Sepehri Shamloo, MD, Department of Electrophysiology, Heart Center Leipzig at University of Leipzig, Strümpellstrasse 39, 04289 Leipzig, Germany, Phone: +49 341 8651413, Fax: +49 341 8651460

Received: 2019-10-11

Accepted: 2019-12-06

Published Online: 2020-01-09

Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.

Research funding: AB, ND, and GH report research grants from Abbott and Boston Scientific to the institution without personal financial benefits. Other authors do not declare any conflict of interest.

Employment or leadership: None declared.

Honorarium: None declared.

Competing interests: The funding organization(s) played no role in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the report for publication.

Conflict of interest statement: AB, ND, and GH report research grants from Abbott and Boston Scientific to the institution without personal financial benefits. Other authors do not declare any conflict of interest.

Citation Information: Diagnosis, 20190072, ISSN (Online) 2194-802X, ISSN (Print) 2194-8011, DOI: https://doi.org/10.1515/dx-2019-0072.

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