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Basic Roles of Sex Steroid Hormones in Wound Repair with Focus on Estrogens (A Review)

Z. Čriepoková / L’. Lenhardt / P. Gál
  • Corresponding author
  • Department for Biomedical Research, East-Slovak Institute of Cardiovascular Diseases, Inc., Košice
  • Department of Pharmacology, Faculty of Medicine, P. J. Šafárik University, Košice
  • Department of Pharmacognosy and Botany, Faculty of Pharmacy, Comenius University, Bratislava The Slovak Republic
  • Institute of Anatomy, 1st Faculty of Medicine, Charles University, Prague The Czech Republic
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Published Online: 2016-04-20 | DOI: https://doi.org/10.1515/fv-2016-0006


Previously, it has been shown that sex hormones, in particular estrogens, play an important role in the regulation of biological processes involved in tissue repair and regeneration. Accordingly, several studies have supported the beneficial properties of hormone replacement therapies (HRT) in postmenopausal models. The present review paper explores the potential for targeted sex steroid HRT as a new therapeutic option for the surgical management of wounds in postmenopausal women and animals.

Keywords: androgens; estrogens; wound healing


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About the article

Received: 2015-11-23

Published Online: 2016-04-20

Published in Print: 2016-03-01

Citation Information: Folia Veterinaria, Volume 60, Issue 1, Pages 41–46, ISSN (Online) 2453-7837, DOI: https://doi.org/10.1515/fv-2016-0006.

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© 2016. This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License. BY-NC-ND 4.0

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