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Folia Veterinaria

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Pathological Alterations in Hepatocytes of Dairy Cows With a Tendency to Emaciation and Fattening

J. Pivko
  • National Agricultural and Food Centre, Research Institute for Animal Production Nitra Hlohovecká 2, 951 41 Lužianky–Nitra The Slovak Republic
/ P. Makovický
  • Czech Centre for Phenogenomics, (BIOCEV), Laboratory of Transgenic Models of Diseases Institute of Molecular Genetics of the ASCR, v. v. i., Vídeňská 1083, 142 20 Prague The Czech Republic
/ A. Makarevich
  • Corresponding author
  • National Agricultural and Food Centre, Research Institute for Animal Production Nitra Hlohovecká 2, 951 41 Lužianky–Nitra The Slovak Republic
  • Email:
/ A. Sirotkin
  • National Agricultural and Food Centre, Research Institute for Animal Production Nitra Hlohovecká 2, 951 41 Lužianky–Nitra The Slovak Republic
/ P. Makovický
  • Selye Janos University in Komárno, Department of Biology, Bratislavská 3322, 945 01 Komárno The Slovak Republic
/ E. Kubovičová
  • National Agricultural and Food Centre, Research Institute for Animal Production Nitra Hlohovecká 2, 951 41 Lužianky–Nitra The Slovak Republic
Published Online: 2016-07-06 | DOI: https://doi.org/10.1515/fv-2016-0019


The aim of this study was to demonstrate the histochemical and histopathological alterations in the livers of cows with a tendency to become emaciated (body condition score - BCS1 and 2) and a tendency to become fattened (BCS4 and 5) in comparison to the cows of average body condition (BCS3) presented as a control. The histochemical analysis (PAS reaction) showed that the influence of emaciation and fattening in our study was manifested by a decreased occurrence of glycogen and a decreased level of the PAS-positive matter in the hepatocytes of dairy cows with BCS1, 2, 4 and 5. An abundant accumulation of lipids in the form of large lipid droplets, liposomes and lipoproteins observed in the hepatocytes of emaciated and fattened (BCS1 and 5) cows may be related to moderate-severe steatosis. These observations suggest a relationship between liver steatosis and the occurrence of lipoproteins in cows with a tendency toward emaciation and fattening.

Keywords: body condition score; hepatocyte; liver; steatosis


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About the article

Received: 2016-05-11

Published Online: 2016-07-06

Published in Print: 2016-06-01

Citation Information: Folia Veterinaria, ISSN (Online) 2453-7837, DOI: https://doi.org/10.1515/fv-2016-0019. Export Citation

© 2016. This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License. (CC BY-NC-ND 4.0)

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