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BY-NC-ND 3.0 license Open Access Published by De Gruyter September 28, 2011

Convenient way of synthesis and crystal structure of 1-[(5-chloro-1H-indol-2-yl)carbonyl]-4-methylpiperazine, a histamine H4 receptor antagonist

  • Dorota Łażewska , Janina Karolak-Wojciechowska , Beata Kolesińska , Zbigniew Kamiński and Katarzyna Kieć-Kononowicz EMAIL logo

Abstract

1-[(5-Chloro-1H-indol-2-yl)carbonyl]-4-methylpiperazine (JNJ 7777120) is the known histamine H4 receptor reference compound. The convenient way of its synthesis and the crystal structure are described.


Corresponding author

Received: 2011-7-31
Accepted: 2011-9-2
Published Online: 2011-09-28
Published in Print: 2011-12-01

©2011 by Walter de Gruyter Berlin Boston

This article is distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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