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Heterocyclic Communications

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Volume 18, Issue 5-6


An efficient one-pot multi-component synthesis of highly functionalized piperidines

Santosh V. Goswami / Prashant B. Thorat / Sudhakar R. Bhusare
Published Online: 2012-12-08 | DOI: https://doi.org/10.1515/hc-2012-0105


A simple, inexpensive and efficient one-pot synthesis of piperidine derivatives was achieved in excellent yield via the three-component reaction of substituted aniline, 1,3-dicarbonyl compound and aromatic aldehyde using phenylboronic acid as catalyst.

This article offers supplementary material which is provided at the end of the article.

Keywords: aniline; aromatic aldehyde; 1,3-dicarbonyl compound; phenylboronic acid; piperidines


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About the article

Corresponding author: Sudhakar R. Bhusare, Department of Chemistry, Dnyanopasak College, Parbhani 431 401, MS, India

Received: 2012-07-26

Accepted: 2012-08-28

Published Online: 2012-12-08

Published in Print: 2012-12-01

Citation Information: , Volume 18, Issue 5-6, Pages 245–248, ISSN (Online) 2191-0197, ISSN (Print) 0793-0283, DOI: https://doi.org/10.1515/hc-2012-0105.

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