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Heterocyclic Communications

Editor-in-Chief: Strekowski, Lucjan

Ed. by Baumstark, Alfons L. / Saczewski, Jaroslaw / Stephens, Chad / Yamada, Hidetoshi

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Volume 22, Issue 6


Heterocyclization of 5,6-disubstituted 3-alkenyl-2-thioxothieno[2,3-d]pyrimidin-4-one with p-alkoxyphenyltellurium trichloride

Mykola Kut / Mikhajlo Onysko / Vasyl Lendel
Published Online: 2016-11-28 | DOI: https://doi.org/10.1515/hc-2016-0169


Electrophilic heterocyclization of 5,6-disubstituted 3-alkenyl-2-thioxothieno[2,3-d]pyrimidin-4-ones by treatment with p-alkoxyphenyltellurium trichlorides leads to annulation of the thiazoline moiety with the formation of 6,7-disubstituted-2-[dichloro-(p-alkoxyphenyl)telluromethyl]-2,3-dihydro-5Н-[1,3]thiazolo[3,2-а]thieno[2,3-d]pyrimidin-5-one hydrochlorides.

Keywords: 3-alkenyl-2-thioxothieno[2,3-d]pyrimidine-4-one; [1,3]thiazolo[3,2-а]thieno[2,3-d]pyrimidin-5-one; electrophilic cyclization; p-alkoxyphenyltellurium trichloride; regioselectivity


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About the article

Received: 2016-10-05

Accepted: 2016-10-31

Published Online: 2016-11-28

Published in Print: 2016-12-01

Citation Information: Heterocyclic Communications, Volume 22, Issue 6, Pages 347–350, ISSN (Online) 2191-0197, ISSN (Print) 0793-0283, DOI: https://doi.org/10.1515/hc-2016-0169.

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