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Helminthologia

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Volume 48, Issue 3 (Sep 2011)

Issues

Lagochilascaris minor: Specific antibodies are related with resistance to experimental infection in A/J strain of mice

M. Prudente
  • Department of Microbiology, Immunology, Parasitology and Pathology, Institute of Tropical Pathology and Public Health, Federal University of Goiás, Goiânia, Brazil
  • Email:
/ J. Freitas
  • Department of Microbiology, Immunology, Parasitology and Pathology, Institute of Tropical Pathology and Public Health, Federal University of Goiás, Goiânia, Brazil
  • Email:
/ E. Ribeiro
  • Department of Microbiology, Immunology, Parasitology and Pathology, Institute of Tropical Pathology and Public Health, Federal University of Goiás, Goiânia, Brazil
  • Email:
/ M. Carvalhaes
  • Department of Microbiology, Immunology, Parasitology and Pathology, Institute of Tropical Pathology and Public Health, Federal University of Goiás, Goiânia, Brazil
  • Email:
Published Online: 2011-09-08 | DOI: https://doi.org/10.2478/s11687-011-0024-4

Abstract

Lagochilascaris minor is the causative agent of human lagochilascariosis, a disease that affects the neck region causing abscesses with eggs, adult parasites and L3/L4 larvae within purulent exudates. Nowadays, mice are considered intermediary hosts for the parasite. In previous study we observed that A/J mice experimentally infected with Lagochilascaris minor showed higher survival ratios than B10.A mice. Now, we denoted that A/J mice (resistant to experimental infection) produced higher levels of IgM, IgG and IgA against the crude extract (excepted for IgM) and secreted/excreted antigens of the parasite; on the other hand, B10.A mice (susceptible to experimental infection) produced higher levels of IgE in the later period of the experimental infection than A/J infected mice.

Keywords: B cells; Lagochilascaris minor; helminth; Immunoglobulin; serology

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About the article

Published Online: 2011-09-08

Published in Print: 2011-09-01


Citation Information: Helminthologia, ISSN (Online) 1336-9083, ISSN (Print) 0440-6605, DOI: https://doi.org/10.2478/s11687-011-0024-4. Export Citation

© 2011 Institute of Parasitology, SAS, Košice, Slovakia. This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License. (CC BY-NC-ND 3.0)

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