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Holzforschung

International Journal of the Biology, Chemistry, Physics, and Technology of Wood

Editor-in-Chief: Faix, Oskar

Editorial Board: Daniel, Geoffrey / Militz, Holger / Rosenau, Thomas / Salmen, Lennart / Sixta, Herbert / Vuorinen, Tapani / Argyropoulos, Dimitris S. / Balakshin, Yu / Barnett, J. R. / Burgert, Ingo / Rio, Jose C. / Evans, Robert / Evtuguin, Dmitry V. / Frazier, Charles E. / Fukushima, Kazuhiko / Gindl-Altmutter, Wolfgang / Glasser, W. G. / Holmbom, Bjarne / Isogai, Akira / Kadla, John F. / Koch, Gerald / Lachenal, Dominique / Laine, Christiane / Mansfield, Shawn D. / Morrell, J.J. / Niemz, Peter / Potthast, Antje / Ragauskas, Arthur J. / Ralph, John / Rice, Robert W. / Salin, Jarl-Gunnar / Schmitt, Uwe / Schultz, Tor P. / Sipilä, Jussi / Takano, Toshiyuki / Tamminen, Tarja / Theliander, Hans / Welling, Johannes / Willför, Stefan / Yoshihara, Hiroshi

12 Issues per year


IMPACT FACTOR 2016: 1.868
5-year IMPACT FACTOR: 1.875

CiteScore 2016: 1.83

SCImago Journal Rank (SJR) 2015: 0.817
Source Normalized Impact per Paper (SNIP) 2015: 0.954

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1437-434X
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Volume 66, Issue 2

Issues

Antithrombotic properties of sulfated wood-derived galactoglucomannans

Aleš Doliška
  • University of Maribor, Faculty of Mechanical Engineering, Institute for Engineering Materials and Design, Slovenia
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/ Stefan Willför
  • Åbo Akademi University, Process Chemistry Centre, Laboratory of Wood and Paper Chemistry, Finland
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/ Simona Strnad
  • University of Maribor, Faculty of Mechanical Engineering, Institute for Engineering Materials and Design, Slovenia
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/ Volker Ribitsch / Karin Stana Kleinschek
  • University of Maribor, Faculty of Mechanical Engineering, Institute for Engineering Materials and Design, Slovenia
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/ Patrik Eklund / Chunlin Xu
  • Åbo Akademi University, Process Chemistry Centre, Laboratory of Wood and Paper Chemistry, Finland
  • Royal Institute of Technology (KTH), AlbaNova University Centre, School of Biotechnology, Sweden
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Published Online: 2011-08-06 | DOI: https://doi.org/10.1515/HF.2011.136

Abstract

Galactoglucomannans (GGMs) are water-soluble polysaccharides released and accumulated in process waters in the production of thermomechanical pulp. The general trend in the forestry industry is moving towards bio-refineries, for example utilizing these hemicelluloses as bioactive substances. At present, there is no industrial use of wood-derived mannans. In this study, GGMs extracted from thermomechanical pulp, as well as further carboxymethyl-ated galactoglucomannans (CM-GGMs), were sulfated to increase their antithrombotic properties. The products were characterized with Fourier transform infrared spectroscopy, nuclear magnetic resonance and capillary electrophoresis. The carbohydrate composition and sulfur amounts were determined. The products’ total charges were determined by polyelectrolyte titrations and their antithrombotic effect was measured based on the activated partial thromboplastin time. The results showed a significant increase in the antithrombotic effect of the sulfated galactoglucomannans from spruce wood and thus a potential new use for wood-derived mannans.

Keywords: activated partial thromboplastin time; anticoagulant; antithrombocity; carboxymethylation; galactoglucomannan; spruce wood; sulfated polysaccharide

About the article

Corresponding author. University of Maribor, Faculty of Mechanical Engineering, Institute for Engineering Materials and Design, Slovenia


Received: 2011-02-07

Accepted: 2011-07-07

Published Online: 2011-08-06

Published in Print: 2012-02-01


Citation Information: Holzforschung, Volume 66, Issue 2, Pages 149–154, ISSN (Online) 1437-434X, ISSN (Print) 0018-3830, DOI: https://doi.org/10.1515/HF.2011.136.

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