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International Journal of Adolescent Medicine and Health

Editor-in-Chief: Merrick, Joav

Editorial Board: Birch, Diana ML / Blum, Robert W. / Greydanus, MD, Dr. HC (Athens), Donald E. / Hardoff, Daniel / Kerr, Mike / Levy, Howard B / Morad, Mohammed / Omar, Hatim A. / de Paul, Joaquin / Rydelius, Per-Anders / Shek, Daniel T.L. / Sher, Leo / Silber, Tomas J. / Towns, Susan / Urkin, Jacob / Verhofstadt-Deneve, Leni / Zeltzer, Lonnie / Tenenbaum, Ariel


CiteScore 2018: 0.79

SCImago Journal Rank (SJR) 2018: 0.350
Source Normalized Impact per Paper (SNIP) 2018: 0.476

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2191-0278
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Volume 30, Issue 1

Issues

Persistence of metabolic syndrome and its impact on glucose metabolism in overweight and obese children and adolescents

Anajás da Silva Cardoso Cantalice
  • Corresponding author
  • Department of Nursing, Federal University of Paraiba (UFPB)
  • Bachelor Program in Nursing, Federal University of Campina
  • Street Espírito Santo, 813, apartment 203, Liberdade, Campina Grande-Paraíba, Brazil, Phone: (+5583) 9119 4460
  • Email
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Inês Fronteira
  • International Health at the Institute of Tropical Medicine and Hygiene, Nova University of Lisbon, Portugal
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Jordana de Almeida Nogueira
  • Department of Nursing and Public Health, School of Ribeirão Preto, São Paulo University
  • Department of Clinical Nursing, Federal University of Paraiba, João Pessoa, Brazil
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Altamira Pereira da Silva Reichert
  • Department of Health of Children and Adolescents, Federal University of Pernambuco
  • Department of Nursing, Federal University of Paraiba, João Pessoa, Brazil
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Carla Campos Muniz Medeiros
  • Department of Health of Children and Adolescents, State University of Campinas (UNICAMP)
  • Department of Public Health, State University of Paraiba, Campina Grande, Brazil
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Neusa Collet
  • Department of Nursing of Public Health and Psychiatry of the Health Sciences Centre (DESPP/CCS)
  • Department of Nursing, Federal University of Paraiba (PPGE/UFPB), João Pessoa, Brazil
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
Published Online: 2016-04-09 | DOI: https://doi.org/10.1515/ijamh-2015-0118

Abstract

Objective:

To verify the effects of metabolic syndrome (MS) and its relation to insulin resistance (IR) in children and adolescents with overweight or obesity after 24 months of follow-up.

Design:

Studies of repeated measures from April 2009 to April 2012. For both measurements, the evaluations performed were anthropometry, MS diagnosis, fasting blood glucose, glucose homeostasis model assessment (HOMA-IR), and insulin level; at a second evaluation, glycated hemoglobin (HbA1c) was used as an additional indicator of glucose metabolism alterations. Logistic regression between syndrome persistence and its components with glucose metabolism alterations was performed for each of its indicators. The SPSS version 17.0 software (95% CI) was used.

Location:

Center for Childhood Obesity, Campina Grande, Brazil.

Subjects:

Children and adolescents (n=133), aged 2–18 years, with overweight or obesity.

Results:

There was a significant decrease in MS during the study period, with persistence of the syndrome in 17.3% of the individuals. The presence of at least one alteration in glucose metabolism occurred in 45.1% of children and adolescents. The systolic and diastolic blood pressure, and the average levels of HOMA-IR showed significant decrease at the end of 24 months (p<0.01), and an elevated waist circumference (WC) remained associated with IR (p<0.01).

Conclusion:

There was observed no relationship of IR or other indicator of glycemic disorders by persistence of MS. An elevated WC remained associated with IR after controlling for the effects of the following variables: gender, age group, and other MS components.

Keywords: adolescent; children; insulin resistance; metabolic syndrome X; obesity

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About the article

Received: 2015-12-04

Accepted: 2016-02-13

Published Online: 2016-04-09


Citation Information: International Journal of Adolescent Medicine and Health, Volume 30, Issue 1, 20150118, ISSN (Online) 2191-0278, DOI: https://doi.org/10.1515/ijamh-2015-0118.

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