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International Journal of Adolescent Medicine and Health

Editor-in-Chief: Merrick, Joav

Editorial Board: Birch, Diana ML / Blum, Robert W. / Greydanus, MD, Dr. HC (Athens), Donald E. / Hardoff, Daniel / Kerr, Mike / Levy, Howard B / Morad, Mohammed / Omar, Hatim A. / de Paul, Joaquin / Rydelius, Per-Anders / Shek, Daniel T.L. / Sher, Leo / Silber, Tomas J. / Towns, Susan / Urkin, Jacob / Verhofstadt-Deneve, Leni / Zeltzer, Lonnie / Tenenbaum, Ariel


CiteScore 2018: 0.79

SCImago Journal Rank (SJR) 2018: 0.350
Source Normalized Impact per Paper (SNIP) 2018: 0.476

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2191-0278
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Volume 31, Issue 4

Issues

Metabolic syndrome in Iranian adolescents with polycystic ovary syndrome

Mohammad H. Dabbaghmanesh
  • Department of Internal Medicine, Endocrine and Metabolism Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Tahereh Naderi
  • Department of Midwifery, student research center, School of Nursing and Midwifery, Shiraz University of Medical Sciences, Shiraz, Iran
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Marzieh Akbarzadeh
  • Corresponding author
  • Maternal–fetal medicine Research Center, Department of Midwifery, School of Nursing and Midwifery, Shiraz University of Medical Sciences, Nemazee Square, P.O. Box: 71345-1359, Shiraz, Iran, Phone: +98 711 36474250, Fax: +98 711 3647425
  • Email
  • Other articles by this author:
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/ Hamidreza Tabatabaee
Published Online: 2017-08-05 | DOI: https://doi.org/10.1515/ijamh-2017-0029

Abstract

Background

Metabolic syndrome (MS) in adolescents is a risk factor for type 2 diabetes and cardiovascular diseases.

Objective

The present study aimed to determine the prevalence of MS in 14–18-year-old girls.

Methods

This analytical case-control study was conducted on 3200 high school students with polycystic ovarian syndrome (PCOS). PCOS was confirmed by an endocrinologist after detection of clinical hyperandrogenism (acne, hirsutism and alopecia) and oligomenorrhea, rejection of hypothyroidism and hyperprolactinemia and performance of abdominal sonography. In the second stage, the prevalence of MS was compared between 70 girls with PCOS and 45 healthy girls using the ATPIII, Cooki and Ferranti scales. The study data were collected using a demographic questionnaire, body mass index (BMI) graph, the WC graph and standard blood pressure graph in adolescents. Then, the data were analyzed using the t-test and the χ2-test.

Results

Based on the Ferranti scale, the prevalence of MS was 10.4% and 0% in the case and control groups, respectively. The highest prevalence was related to hyperandrogenism and polycystic ovaries phenotype (11.6% vs. 0%, p = 0.05). Based on the Cooki and ATPIII scales, the prevalence of this disorder was 4.1% in the case group and 0.67% in the control group, with the highest rate being related to hyperandrogenism, oligomenorrhea and polycystic ovaries phenotype (7.5% vs. 0%, p = 0.28).

Conclusion

In comparison to the control group, the prevalence of MS in the patients with PCOS was 10-fold higher according to the Ferranti scale and nearly 3.5-fold higher based on the Cooki and ATPIII scales. Thus, long-term follow-up is suggested in these patients.

Keywords: adolescent; metabolic syndrome; polycystic ovarian syndrome

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About the article

Received: 2017-02-17

Accepted: 2017-05-10

Published Online: 2017-08-05


Authors’ Contribution: T. Naderi, M. Akbarzadeh and M.H. Dabbaghmanesh conceived of the study and participated in its design and coordination and helped to draft the manuscript. T. Naderi collected the data. M. Akbarzadeh and H.R. Tabatabaee performed the statistical analysis. T. Naderi and M. Akbarzadeh made critical revisions to the paper and translated it into English. All authors read and approved the final version of the paper.

Financial disclosure: There is no financial disclosure.

Funding/Support: This study was financially supported by Student Research Committee of Shiraz University of Medical Sciences Shiraz, Iran.


Citation Information: International Journal of Adolescent Medicine and Health, Volume 31, Issue 4, 20170029, ISSN (Online) 2191-0278, DOI: https://doi.org/10.1515/ijamh-2017-0029.

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