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International Journal of Adolescent Medicine and Health

Editor-in-Chief: Merrick, Joav

Editorial Board: Birch, Diana ML / Blum, Robert W. / Greydanus, MD, Dr. HC (Athens), Donald E. / Hardoff, Daniel / Kerr, Mike / Levy, Howard B / Morad, Mohammed / Omar, Hatim A. / de Paul, Joaquin / Rydelius, Per-Anders / Shek, Daniel T.L. / Sher, Leo / Silber, Tomas J. / Towns, Susan / Urkin, Jacob / Verhofstadt-Deneve, Leni / Zeltzer, Lonnie / Tenenbaum, Ariel


CiteScore 2018: 0.79

SCImago Journal Rank (SJR) 2018: 0.350
Source Normalized Impact per Paper (SNIP) 2018: 0.476

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2191-0278
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Human adenovirus-36 seropositivity and obesity among Midwestern US adolescents

Aneesh K. Tosh
  • Corresponding author
  • University of Missouri School of Medicine, 400 N. Keene St. Suite 102G Columbia, MO 65201, USA, Phone: 1-573-884-9684, Fax: 1-573-884-5226
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/ Mollie G. Wasserman / Matthew T. McLeay II / Sara K. Tepe
Published Online: 2017-11-23 | DOI: https://doi.org/10.1515/ijamh-2017-0126

Abstract

Objective

Human adenovirus-36 (Ad-36) infection has been implicated as a risk factor for obesity. This study aims to measure Ad-36 antibody prevalence among obese and healthy-weight Midwestern US adolescents.

Methods

Obese and healthy-weight subjects 10–18 years of age attending an adolescent clinic in Missouri, USA, were tested for Ad-36 antibodies via ELISA assay. All subjects were measured for height and weight to determine body mass index (BMI). χ2 analysis was used to compare Ad-36 antibody prevalence between the two groups.

Results

Ad-36 antibodies were tested on 41 obese and 37 control subjects. The subjects’ mean age at the time of sample collection was 15.6 years (SD 2.0). Ad-36 antibody prevalence was 43.9% among the obese group and 21.6% among the control group (p = 0.038).

Discussion

The findings show that statistically more obese Missouri adolescents test positive for Ad-36 antibodies than their healthy-weight peers, consistent with previous findings suggesting a correlation between Ad-36 infection and obesity.

Keywords: adenovirus; adolescent; obesity

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About the article

Received: 2017-07-18

Accepted: 2017-08-20

Published Online: 2017-11-23


Funding source: This research was supported by the Forrest O. Sears and Leda J. Sears Trust awarded to A.K.T.

Conflict of interest: The authors have no conflicts, real or perceived.


Citation Information: International Journal of Adolescent Medicine and Health, 20170126, ISSN (Online) 2191-0278, DOI: https://doi.org/10.1515/ijamh-2017-0126.

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