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International Journal of Adolescent Medicine and Health

Editor-in-Chief: Merrick, Joav

Editorial Board: Birch, Diana ML / Blum, Robert W. / Greydanus, MD, Dr. HC (Athens), Donald E. / Hardoff, Daniel / Kerr, Mike / Levy, Howard B / Morad, Mohammed / Omar, Hatim A. / de Paul, Joaquin / Rydelius, Per-Anders / Shek, Daniel T.L. / Sher, Leo / Silber, Tomas J. / Towns, Susan / Urkin, Jacob / Verhofstadt-Deneve, Leni / Zeltzer, Lonnie / Tenenbaum, Ariel


CiteScore 2018: 0.79

SCImago Journal Rank (SJR) 2018: 0.350
Source Normalized Impact per Paper (SNIP) 2018: 0.476

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2191-0278
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The association between iron deficiency anemia and febrile seizure

Parviz Karimi
  • Department of Pediatric Diseases, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran
  • Other articles by this author:
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/ Koroush Sayehmiri
  • Department of Biostatistics, Psychosocial Injuries Research Center, Ilam University of Medical Sciences, Ilam, Iran
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/ Milad Azami
  • Student Research Committee, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran
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/ Zeinab Tardeh
  • Corresponding author
  • Student Research Committee, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran, Phone: +9337416255
  • Email
  • Other articles by this author:
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Published Online: 2019-07-13 | DOI: https://doi.org/10.1515/ijamh-2019-0083

Abstract

Objective

Different studies have reported contradictory results regarding the relationship between iron deficiency anemia (IDA) and febrile seizure (FS). The present study was conducted to determine the effect of IDA on FS in children.

Patients and methods

This case-control study was conducted among 52 children with FS (the case group) and 18 children with afebrile seizures and 51 children with fever without seizures in the age range of 6 months to 5 years admitted to the pediatric ward of Imam Khomeini Hospital in Ilam from March 2016 to January 2017. Patients were selected using the convenience sampling method. Red blood cell (RBC) count as well as measurement of hemoglobin (Hb), hematocrit (Hct), ferritin, mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH) and mean corpuscular hemoglobin concentration (MCHC) levels were performed in all patients. The collected data were analyzed using SPSS16 software.

Results

A total of 34.6% in the FS group, 66.7% in the afebrile seizure group and 41.2% in the fever without seizure group suffered from IDA, which was not statistically significant between the three groups. Hb, Hct and RBC levels were higher in the case group and MCV, MCH, MCHC levels in the case group were lower than those in the control group. The odds ratio (OR) for FS compared to the febrile group was 0.756 [95% confidence interval (CI) = 0.34–1.68; p = 0.493] and that for FS compared to seizure was 0.265 (95% CI = 0.085–0.823; p = 0.022).

Conclusions

This study showed that IDA may have protective effects on the onset of FS, and based on the results, IDA is more common in children with afebrile seizures. Further and more comprehensive studies are recommended.

Keywords: adolescent; IDA; nurse

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About the article

Received: 2019-04-10

Accepted: 2019-04-28

Published Online: 2019-07-13


Citation Information: International Journal of Adolescent Medicine and Health, 20190083, ISSN (Online) 2191-0278, DOI: https://doi.org/10.1515/ijamh-2019-0083.

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