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The International Journal of Biostatistics

Ed. by Chambaz, Antoine / Hubbard, Alan E. / van der Laan, Mark J.


IMPACT FACTOR 2018: 1.309

CiteScore 2018: 1.11

SCImago Journal Rank (SJR) 2018: 1.325
Source Normalized Impact per Paper (SNIP) 2018: 0.715

Mathematical Citation Quotient (MCQ) 2018: 0.03

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1557-4679
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Two-Sample Tests of Area-Under-the-Curve in the Presence of Missing Data

John Spritzler / Victor G DeGruttola / Lixia Pei
Published Online: 2008-01-17 | DOI: https://doi.org/10.2202/1557-4679.1068

The commonly used two-sample tests of equal area-under-the-curve (AUC), where AUC is based on the linear trapezoidal rule, may have poor properties when observations are missing, even if they are missing completely at random (MCAR). We propose two tests: one that has good properties when data are MCAR and another that has good properties when the data are missing at random (MAR), provided that the pattern of missingness is monotonic. In addition, we discuss other non-parametric tests of hypotheses that are similar, but not identical, to the hypothesis of equal AUCs, but that often have better statistical properties than do AUC tests and may be more scientifically appropriate for many settings.

Keywords: AUC; bias; missing data; test

About the article

Published Online: 2008-01-17


Citation Information: The International Journal of Biostatistics, Volume 4, Issue 1, ISSN (Online) 1557-4679, DOI: https://doi.org/10.2202/1557-4679.1068.

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