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The International Journal of Biostatistics

Ed. by Chambaz, Antoine / Hubbard, Alan E. / van der Laan, Mark J.

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Principal Stratification -- a Goal or a Tool?

Judea Pearl
Published Online: 2011-03-30 | DOI: https://doi.org/10.2202/1557-4679.1322

Principal stratification has recently become a popular tool to address certain causal inference questions, particularly in dealing with post-randomization factors in randomized trials. Here, we analyze the conceptual basis for this framework and invite response to clarify the value of principal stratification in estimating causal effects of interest.

Keywords: causal inference; principal stratification; surrogate endpoints; direct effect; mediation

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Published Online: 2011-03-30

Citation Information: The International Journal of Biostatistics, ISSN (Online) 1557-4679, DOI: https://doi.org/10.2202/1557-4679.1322.

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©2011 Walter de Gruyter GmbH & Co. KG, Berlin/Boston. Copyright Clearance Center

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