The International Journal of Biostatistics
Ed. by Chambaz, Antoine / Hubbard, Alan E. / van der Laan, Mark J.
IMPACT FACTOR 2015: 0.667
5-year IMPACT FACTOR: 1.188
SCImago Journal Rank (SJR) 2015: 0.495
Source Normalized Impact per Paper (SNIP) 2015: 0.180
Impact per Publication (IPP) 2015: 0.319
Mathematical Citation Quotient (MCQ) 2015: 0.04
A Refreshing Account of Principal Stratification
1University of Florence
2University of Florence
Citation Information: The International Journal of Biostatistics. Volume 8, Issue 1, ISSN (Online) 1557-4679, DOI: https://doi.org/10.1515/1557-4679.1380, April 2012
- Published Online:
Pearl (2011) invites researchers to contribute to a discussion on the logic and utility of principal stratification in causal inference, raising some thought-provoking questions. In our commentary, we discuss the role of principal stratification in causal inference, describing why we view the principal stratification framework as useful for addressing causal inference problems where causal estimands are defined in terms of intermediate outcomes. We focus on mediation analysis and principal stratification analysis, showing that they generally involve different causal estimands and answer different questions. We argue that even when principal stratification may not answer the causal questions of primary interest, it can be a preliminary analysis of the data to assess the plausibility of identifying assumptions. We also discuss the use of principal stratification to address issues of surrogate outcomes. Our discussion stresses that a principal stratification analysis should account for all the principal strata and evaluate the distributions of potential outcomes in each of the principal strata. To this end, we view a Bayesian analysis particularly suited for drawing inference on principal strata membership and principal strata effects.
Here you can find all Crossref-listed publications in which this article is cited. If you would like to receive automatic email messages as soon as this article is cited in other publications, simply activate the “Citation Alert” on the top of this page.