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Innovative Neurosurgery

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Transsphenoidal endoscopic skull base surgery: state of the art and future perspective

Aaron R. Cutler
  • Brain Tumor Center and Pituitary Disorders Program, John Wayne Cancer Institute at Saint John’s Health Center, Santa Monica, CA, USA
  • Other articles by this author:
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/ Garni Barkhoudarian
  • Brain Tumor Center and Pituitary Disorders Program, John Wayne Cancer Institute at Saint John’s Health Center, Santa Monica, CA, USA
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Chester F. Griffiths
  • Brain Tumor Center and Pituitary Disorders Program, John Wayne Cancer Institute at Saint John’s Health Center, Santa Monica, CA, USA
  • Pacific Eye and Ear Specialists, Los Angeles, CA, USA
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/ Daniel F. Kelly
  • Corresponding author
  • Brain Tumor Center and Pituitary Disorders Program, John Wayne Cancer Institute at Saint John’s Health Center, Santa Monica, CA, USA
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Published Online: 2013-01-14 | DOI: https://doi.org/10.1515/ins-2012-0011

Abstract

Given refinements in endoscopic image quality, instrumentation, surgical navigation, skull base closure techniques and anatomical understanding, the endonasal endoscopic approach is now a well-accepted and widely utilized technique for removal of many if not most midline ventral skull base tumors. Pituitary adenomas and Rathke’s cleft cysts (RCCs) constitute the majority of lesions removed via this route; however, craniopharyngiomas, clival chordomas, midline meningiomas and other benign and malignant skull base tumors are now increasingly removed by this approach. Herein we describe the evolution of the endonasal endoscopic technique, its current use for sellar and midline skull base tumors and potential for future innovation.

Keywords: Chordoma; craniopharyngioma; endoscopic surgery; meningioma; pituitary adenoma; skull base surgery

About the article

Corresponding author: Daniel F. Kelly, MD, Brain Tumor Center and Pituitary Disorders Program, John Wayne Cancer Institute at Saint John’s Health Center, 2200 Santa Monica Blvd., Santa Monica, CA 90404, USA, Tel.: +1 310 582–7450, Fax: +1 310 582–7495


Received: 2012-10-23

Accepted: 2012-11-28

Published Online: 2013-01-14

Published in Print: 2013-02-01


Citation Information: Innovative Neurosurgery, Volume 1, Issue 1, Pages 15–35, ISSN (Online) 2193-5238, ISSN (Print) 2193-522X, DOI: https://doi.org/10.1515/ins-2012-0011.

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©2013 by Walter de Gruyter Berlin Boston.Get Permission

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